In conjunction with the PhysioMimix™ OOC lab-benchtop ready microphysiological (MPS) system, MPS-LC12 consumable plates are used to culture advanced 3D in vitro organ-on-a-chip models that provide fast, accurate and clinically translatable human data for improving the predictability of drug discovery.
Arranged in a multi-well format, the MPS-LC12 consumable plate features 12 independent wells that represent mini bioreactors. Embedded into each well are three-dimensional scaffolds. During experiments, scaffolds are continually perfused by oxygen and nutrients in cell culture medium, creating the ideal culture conditions for 3D microtissue formation. For example, by co-culturing primary liver cells in MPS-LC12 consumable plates, it is possible to mimic the architecture of the human liver capillary bed under perfusion.
Validated applications for MPS-LC12 consumable plates include:
MPS-LC12 consumable plates are:
Contact CN Bio for more information about 3D in vitro models validated using MPS-LC12 consumable plates, or guidance designing your own bespoke tissue or organ mimics.