Gilson VERITY Compact CPC System
The VERITY Compact CPC System combines a PLC Purification System with a centrifugal partition chromatography (CPC) system for high-level target compound purification.
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The VERITY® Compact CPC System combines a PLC Purification System with a centrifugal partition chromatography (CPC) system for high-level target compound purification. This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns to streamline your workflow and allow you to quickly isolate specific molecules with high yields and purity.
Targeted purification of an antimalarial compound from <em>Artemisia Annua L.</em> extract using the VERITY CPC LAB MS system
The extract of the leaves of Artemisia Annua L. is used in ancient Chinese herbal therapy for malarial fevers. Artemisinin has been identified as an active antimalarial compound, and recently, it has been found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium falciparum.
In this application note, Gilson presents experimental data on the use of centrifugal partition chromatography (CPC) coupled with a preparative liquid chromatography system equipped with UV-DAD and mass spectrometry (MS) detectors to isolate active compounds from complex mixtures. Mass-directed CPC purification allows individual targeting and selective collection of molecules based on their mass-to-charge ratio, even for those that do not provide a UV signal. Because the VERITY® CPC Lab MS System does not denature fragile molecules, it is an ideal choice for natural extract fractionation and natural compound purification.
Centrifugal partition chromatography: Isolation of mono-aromatic compounds from oxidatively depolymerized lignin
Watch this on-demand webinar to explore the challenges of lignin valorization in the modern biorefinery
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VERITY® 3240
Gilson, Inc.The VERITY® 3240 High Pressure Binary Gradient Pump is designed for semi-preparative to preparative purification. It provides an economical and compact pumping solution for preparative purification on 10 to 50 mm ID columns thanks to its large dynamic flow range up to 150mL/min. and pressure up to 420 bar (6090 psi).