CyBio SELMA
Automated Pipetting with 96- and 384-Well Microplates
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Good instrument.
Feeding cells in 96-well plates
This instrument was fairly easy to use, and made media changes in 96-well plates much faster than if they were done manually.
Review Date: 7 Dec 2020 | Analytik Jena GmbH+Co. KG
The CyBio® SELMA is a semi-automatic 96- or 384-fold pipettor with minimal required space for fast and precise processing of 96- and 384-well microplates without the need of programming.
- Simple and intuitive handling with touch screen enables the saving of methods and method parameters incl. pipetting speed, volumes and heights
- Easy and fast tip changing with ready to use CyBio® TipTrays
- Error-free and reproducible results due to highly precise 96/384 parallel pistons and high throughput proven “tip sealing” technology
An open design with two working positions allow the processing of any SBS compliant labware as well as the use of external devices like shakers, vacuum chambers, heating adapters, etc.
Applications like replication and reformatting of microplates, as well as serial dilutions can be executed in seconds. CyBio® SELMA is a semi-automatic bench-top pipettor based on well proven HTS technologies of CyBio AG and offers highest precision and robustness. With 96 or 384 disposable tips, all 96 and 384-well microplate formats can be filled in seconds. Automatic tip sealing avoids laborious adjustments and preloaded CyBio® TipTrays guarantee rapid execution within seconds. Custom-racked tip magazines enable even the omission of individual columns and thus, give the user more options to create individual dispense patterns specific to their assay requirements.
CyBio® SELMA is amazingly easy to use via a modern touch screen. All manual operating tasks such as tip change and plate change are shown on the display. Microplates of varying heights and well dimensions can be handled easily by CyBio® SELMA as the pipetting head position is adjusted via a simple dial. Any adjustments such as dispense height, volume and pipetting speed are memorized, retrievable and changeable for regular use anytime.
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Save time and increase accuracy with CyBio liquid handling
Explore Analytik Jena’s CyBio liquid handling systems, designed to seamlessly integrate into your laboratory workflows with exceptional ease of use and rapid processing capabilities. From entry-level models to fully automated robotic systems, CyBio liquid handling systems cater to a diverse range of needs and deliver top-tier precision and reliability.
Precision of the CyBi®-SELMA 96, 250 μl
CyBi®-SELMA is a semi-automatic pipettor for quick, precise and reproducible processing of 96-well and 384-well microplates. This application note summarizes CyBio AG’s liquid handling experience with the CyBi®-SELMA 96, 250 μl. The data demonstrate pipetting parameters for a broad range of customer specific applications and show the volume limits which vary with pipetting conditions and liquids.
Implementation of Cisbio’s HTRF® M1 Muscarinic Receptor Related Assays on CyBio Liquid Handling Solutions for Small and High Throughput
As a reference screening technology, HTRF® is commonly used by drug discovery researchers during high throughput screening operations. Besides this, HTRF “mix & read” assays are increasingly run under medium or lower throughput as an alternative to other technologies, bringing more flexibility, robustness and easiness in daily lab practice. For the purpose of the present study, Muscarinic M1 receptor was selected and assessed with different CyBio liquid handling devices for small and high throughput. Both HTRF assays were performed with the semi-automatic pipettor CyBi-SELMA® 96/25 µl which is a reliable tool to handle low sample numbers. Selected pharmacological results were checked against data generated by the CyBio robotic workstation for HTS to compare the reliability and reproducibility of both CyBio liquid handling stations at different automation levels.
Semi-Automated Genomic DNA Extraction from Plant with CyBi®-SELMA 96/1000 μl Using NucleoSpin® 96 Plant II Kit
This application note describes the use of the CyBi® SELMA 96/1000 μl to automate MACHEREY-NAGEL NucleoSpin 96 Plant II technology for plant genomic DNA extraction. The use of a 96-well pipetting head enables a rapid automated procedure while maintaining the purification technology’s highly reliable performance.
Implementation of Cisbio's HTRF® M1 Muscarinic Receptor Related Assays on Cybio Liquid Handling Solutions for Small and High Throughput
The application note illustrates how different M1-related binding and functional HTRF assays were implemented and run successfully using the CyBi® SELMA 96/25μl and a completely integrated CyBio robotic workstation. With both liquid handling systems, comparable pharmacological results were achieved.
Implementation of Cisbio's HTRF® M1 muscarinic receptor related assays on CyBio liquid handling solutions for small and high throughput
The present study illustrates, how different Cisbio HTRF assays were implemented and run successfully using CyBio’s liquid handling solutions for different automation levels. The CyBi®-SELMA is the optimal semi-automated pipettor to handle precisely lower HTRF assay sample numbers thus ideally suited for smooth transfer from assay development to screening. The pharmacological results agreed with thus obtained with a completely integrated CyBio robotic workstation. It could be demonstrated, that Cisbio HTRF assays and CyBio liquid handling form a perfect match to offer a straightforward and flexible automated assay platform for small troughput analysis as well as for drug discovery at the HTS level.
Cardiotoxicity of iCell® Cardiomyocytes Using the CyBi®-SELMA 96, 250 μl Semi-automated Pipettor
In this study, a 96, 250 μl semi-automated pipettor from CyBio AG was evaluated through media changes and compound dosing in a cell viability assay. The assay tests the cardiac cytotoxicity of a series of compounds on the viability of iCell® Cardiomyocytes.
CyBio Automation: Breadth of CyBio Integration Concepts
This video demonstrates how CyBio can help to maximize your productivity at every level of laboratory automation.
CyBio® Introduces the CyBi® SELMA and the New CyBi®-QuadStack
Watch this interview to learn about the CyBi® SELMA ideal for 96/1000µl volumes. The system is a precise semi automated pipettor requiring user intervention. Debra Conway from CyBio® also introduces the CyBi®-QuadStack which, with a circular design, is able to increase microplate capacity of up to 232 microplates in 4 stacks. ELRIG 2011 Interview.
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CyBio Tips
Analytik Jena GmbH+Co. KGCyBio provide a broad range of CyBio Tips, covering different volume ranges and several tip lengths. You may select from CyBio Tips in the following three qualities: standard, pre-sterilized or pre-sterilized, PCR certified with and without filter. All CyBio Tips have been designed, manufactured and quality inspected with respect to automation requirements, in turn permitting unattended, precise and highly reproducible sample processing. The Tips are available as disposable magazines CyBio TipTrays and CyBio RoboTipTrays that are preloaded with tips for 96-/ 384-channel pipetting heads, allowing tip changing manually or automatically. For applications that need single channel, column- or row-wise pipetting the CyBio Tips are available in CyBio TipBoxes.
