SyncroPatch 384 by Nanion Technologies GmbH
Status:
Reviewer
Member since: 2022
Organization: SB drug discovery
-
- Ease of use
- After sales service
- Value for money
Great machine, users friendly.
Application Area: Electrophysiology
"Great tool to test compound libraries on specific targets. Different functions can be used to investigate further the activity of ion channels"
Review date: 12 Jan 2022 | SyncroPatch 384
Status:
Reviewer Member since: 2022
Organization: Rajiv Gandhi Centre for Biotechnology
-
- Ease of use
- After sales service
- Value for money
Great results and very reliable.
Application Area:Patch clamp, characterization of ion channels
"Very effective, reliable and user friendly."
Review date: 12 Jan 2022 | SyncroPatch 384
Status:
Reviewer Member since: 2022
Organization: selectION Inc.
-
- Ease of use
- After sales service
- Value for money
Excellent device, perfect service and team.
Application Area:Ion Channel Discovery
"Device provides easy to use electrophysiological testing and a high-throughput combined with data reliability. Nanion´s product support and development is outstanding. "
Review date: 11 Jan 2022 | SyncroPatch 384
Status:
Reviewer Member since: 2012
Organization: University of Zurich
-
- Ease of use
- After sales service
- Value for money
The most valuable tool for characterisation of red blood cell ion channels!
Application Area:Red blood cell electrophysiology
"This is the only automated high throughput patch clamp setup that allows to resolve cell-to-cell differences and characterise the fractions of red blood cells with different properties in human blood."
Review date: 11 Jan 2022 | SyncroPatch 384
Status:
Reviewer Member since: 2022
Organization: Sanquin Research
-
- Ease of use
- After sales service
- Value for money
I cannot wait to have the machine available for our research!
Application Area:Measuring ion transport over cell membranes
"The transport of ions over the cell membrane transmits important signals to almost all cell types. It is essential for the survival and function of cells and thereby for our existence and in disease and therapy. The SyncroPatch allows us to study how transport of ions over the cell membrane is regulated in health and disease: much, much more efficient and reliable than the previously available technology. An important breakthrough!"
Review date: 11 Jan 2022 | SyncroPatch 384
Status:
Reviewer Member since: 2021
Organization: University of Michigan. Life Science Institute
-
- Ease of use
- After sales service
- Value for money
Outstanding in drug discovery development!
Application Area:Drug Discovery & Development
"Innovation toward cost effectiveness makes the 384 Automated Patch Clamp System a way to get more reliable results in a short time."
Review date: 09 Nov 2021 | SyncroPatch 384
Status:
Reviewer Member since: 2021
Organization: SB Drug Discovery
-
- Ease of use
- After sales service
- Value for money
Reliable, flexible and easy-to-use automated E'phys system! Highly recommended!
Application Area:Ion channel electrophysiology
"At SB Drug Discovery we have found the SyncroPatch to be an easy-to-use platform that has allowed us to quickly characterise a broad range of voltage-gated and fast ligand-gated ion channels while further improving our efficiency through increased automation. The flexibility offered by the SyncroPatch has enabled us to conduct complex screening assays designed to meet customer demands and expand our ion channel drug discovery capabilities."
Review date: 19 Jan 2021 | SyncroPatch 384
Status:
Reviewer Member since: 2020
Organization: University of Copenhagen
-
- Ease of use
- After sales service
- Value for money
Great instrument that made my PhD research possible.
Application Area:Functional screening of ion channel variants (ASIC1a)
"I had the chance to use the SyncroPatch for parts of my PhD research, enabling the high-throughput functional characterization of over 300 different ASIC1a variants. Working with transiently transfected cells that were FACS-sorted before the patch-clamp experiments, I didn't expect perfect seals, but I still got good quality data and reproducible results that formed the basis for my PhD project. I measured CRCs for activation and steady-state desensitization, as well as peptide modulation of the channel, and got fantastic support from Søren Friis both with technical questions and assay design. The SyncroPatch and its software are easy to use and allow for versatile assay design. The team at Nanion goes out of their way to help with all questions and requests that come up, and they host fantastic user meetings for idea exchange. After four years using the SyncroPatch, I can highly recommend it."
Review date: 20 Nov 2020 | SyncroPatch 384
The new SyncroPatch 384 is a revolutionary automated patch clamp system consisting of a patch clamp module integrated into the state-of-the-art pipetting robot Biomek i5. With 384 amplifier channels and a 384-pipetting head, all 384 cells are recorded in parallel, resulting in a throughput of 20,000 data points per day. With its ease-of-use and open design, the SyncroPatch 384 supports full automation and integration into HTS environments.
But the SyncroPatch 384 is more than a high throughput screening system and can be implemented into all your electrophysiology projects, whatever your throughput needs. The 32-well mode of operation is ideal for smaller screening projects and academic research and takes full advantage of the economical price of the NPC-384 chip. Choose the number of parallel recordings that you need in multiples of 32, you can use the remaining wells over several days. Alternatively, you can use the SyncroPatch 384 in unattended mode for fully automated experiments for over 8 hours.
The exceptional data quality and flexibility have made the SyncroPatch 384 the preferred 384-channel automated patch clamp system for global pharmaceutical companies, CROs and academic institutions alike.
Additional information about the SyncroPatch 384 can be found at: https://www.nanion.de/en/products/syncropatch-384.html
Product Overview
