Sphera™
Discrete Droplet Dispensing™, ONLY cooler! Unleash the power of discrete droplet dispensing to enable superior performance. Better Yield. Higher Throughput. Expanded Dynamic Range. BioDot’s platform design expertise applied to the Lyobead formation challenge in an established product.
Sphera
Sphera 2
Sphera 3
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Product Features:
- Volumes: 2μL- 30μL as a single drop
- Volume precision of <3% CV
- High-speed, non-contact dispensing
- Bulk Dispense Scalable from R&D to production environments
- Printing with “Step-and-Repeat” and “On-the-Fly” mode"
- Minimization of cold-chain logistics and costs
- Lyobeads are thermally stable with a long shelf life
- Lyobeads have lower risk of contamination
- Lyobeads have single unit reconstitution
Applications:
- Enzymes
- Buffers
- Chromophores
- Probiotics
- Vaccines
- Calibrators
- PCR assays
- Antibodies
- Diagnostic reagents
- Magnetic/Fluorescent Particles
Brochures
Sphera™ lyobead dispensing system data sheet
Discover the key benefits of the Sphera™ lyobead dispensing system. Capable of dispensing 2 to 30μL as a single drop and scalable from R&D to production environments, they Sphera™ can be used for the following applications including diagnostic reagents, bacterial vaccines, PCR assay buffers and chromophores, antibodies, probiotics, as well as enzymes and substrates.
Lyophilized beads: Efficient, scalable, production
In this brochure, BioDot addresses challenges in producing lyophilized beads at the microliter scale using conventional dispensing technologies. Conventional methods often result in inconsistent drop volumes, poor bead morphologies, and low throughput, leading to decreased yield and increased manufacturing costs. BioDot enables non-contact fluid dispensing in microliter, nanoliter, and picoliter volumes, reliably, accurately, and quickly, and are capable of handling fluid viscosities from 0.5 cPs to 10 cPs.
Discrete droplet dispensing
In this product brochure, BioDot introduces the Sphera™, a lyobead formation system which dispenses precise and accurate droplet spheres into an onboard liquid nitrogen bath.
Miniaturize to maximize: Precision liquid handling & dispensing for discovery and applied research
To overcome barriers associated with manual pipetting, researchers are increasingly turning to miniaturized liquid handling – dispensing in the picoliter to microliter range – to enhance efficiency, reproducibility, and speed, while cutting costs and waste.
In this SelectScience guide, explore a range of precision liquid handling solutions from BioDot Inc. that are transforming discovery and applied research, from sample preparation for PCR and mass spectrometry, to assay development, diagnostics, and biosensor production.
Whether you are optimizing an assay, developing a diagnostic platform, or engineering high-value bioproducts, this guide offers practical insight into how miniaturized liquid handing can enable your lab to do more with less.
Download the eBook to learn about solutions for:
- PCR and molecular workflows
- Cytogenetics
- Lyobead formation
- Mass spectrometry
- Biosensors and diagnostics
You will find application notes, brochures, and datasheets that will help you learn more about potential solutions for your lab. Plus, read case studies to hear how BioDot precision liquid handling technology is transforming workflows across animal health, cancer diagnosis, and point-of-care test manufacturing.
30 years of Discrete Droplet Dispensing innovation
In this application note, BioDot reflects on 30 years of groundbreaking science, taking a look at how some of its customers are implementing BioDot technologies, and the positive impacts they continue to have for lab technicians, researchers or clinicians and, in many cases, healthcare systems and their patients.
Liquid reagents to lyophilized beads
There are several advantages in moving away from using liquid reagents in point of care testing kits and microfluidics devices. In this application note, BioDot introduces its Sphera™ platform for lyobead formation.
Advancing lab access to lyophilized bead technology
Hear from Brian Kirk, VP of Product Development, as he discusses BioDot’s mission and the growing role of microfluidics in the lab. Learn why lyophilized beads are gaining traction in diagnostics and pharma, and how the Sphera™ Discovery is set to bring lyobead production from larger manufacturing into the lab. Kirk also shares his vision for the future impact of lyobead technology on these industries.
This video was filmed at SLAS 2025.
