The use of alkylamine ion pairing reagents and perfluorinated alcohols in the analysis of oligonucleotides by LC-MS techniques has been the mainstay in characterization and quantitation methods for synthetic oligonucleotides for decades. Often, analytical chemists default to relatively high concentrations of both.
But what concentration of ion pairs do you need for optimal chromatographic performance? And, how much does perfluorinated alcohol concentration contribute to electrospray ionization efficiency?
In this webinar, Brian Rivera, Global Product Manager for Bioseparations Products at Phenomenex, explores modulation of both mobile phase additives, including different alkylamine ion pair options outside of the commonly used triethylamine.
Key learning objectives:
Who should attend?
The live webinar takes place on Tuesday, June 16, 2020, at:
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