8 Exclusive Clinical Mass Spectrometry Interviews

Read exclusive interviews from experts in healthcare settings around the world, to discover how mass spectrometry is improving clinical diagnostics

9 Feb 2018
Sonia Nicholas
Managing Editor and Clinical Lead

More and more clinical laboratories are adopting mass spectrometry into their everyday workflow. In this article, find out how clinical thought leaders are using mass spectrometry to provide better diagnostics and improve patient care.

Image credit: Mr.Smith-Chetanachan © 123rf.com


1. Robust Gas Chromatography Optimizes Blood Alcohol and THC Analyses at St. Olavs Hospital, Norway

Gas chromatography-based analysis is widely used to determine alcohol (ethanol) levels in the body. This is necessary to find out if a person is legally intoxicated, or driving under the influence of a variety drugs (DUID). In this interview, find out how chemists from the Department of Clinical Pharmacology, St. Olavs Hospital, Norway, are using gas chromatography to enhance their DUID investigations. 

2. ICP-Mass Spectrometry Leads the Way in Clinical Biochemistry

Dr Alex Lawson, principal clinical scientist, Birmingham Heartlands Hospital, UK, discusses the use of inductively coupled plasma mass spectrometry in clinical science research. 

3. Mass Spectrometry Inventor, Alexander Makarov, Explains How State-of-the-Art MS is Being Utilized in World Leading Anti-Doping Laboratories

The Hong Kong Jockey Club is one of the largest and most well-respected flat racing organizations in the world. The Club has a world-class drug-testing facility, on site at the Sha Tin Racecourse. This internationally-accredited laboratory uses state-of-the-art mass spectrometry to test for the presence of prohibited substances. In this interview, SelectScience® speaks to the world famous mass spectrometry inventor, Alexander Makarov to learn more. 

4. Why Good Service Engineers are Vital for a Smooth-Functioning Clinical Lab

The Dartmouth-Hitchcock health center located in New Hampshire, USA, serves the local community with professional medical support and clinical tests. In this interview, Tara Jackson, a clinical technologist and researcher at Dartmouth-Hitchcock, discusses the instruments they use for processing hundreds of samples every day, and how they keep the clinical lab functioning smoothly when technical issues are encountered. 

5. Streamlined Clinical Mass Spectrometry Workflow at Imperial College Healthcare

Emma Walker is a consultant clinical scientist, and specialty lead for diagnostic endocrinology at North West London Pathology, hosted by Imperial College Healthcare NHS Trust, UK. Her laboratory has recently implemented a fully-automated liquid chromatography tandem mass spectrometry (LC-MS/MS) workflow. SelectScience® speaks to Emma to learn more about the service. 

6. A Homegrown Team of Clinical Mass Spectrometry Specialists

Find out how the busy UK biochemistry department, at the University Hospital of South Manchester, UK, has implemented mass spectrometry for clinical practice, and improved specificity and cost-efficiency of its service 

7. Optimizing Clinical LC-MS/MS Workflow at The University-Hospital Padova

As increasing numbers of clinical laboratories seek to take advantage of the precision and accuracy of mass spectrometry (MS), effective workflows are essential. The University-Hospital Padova MS workflow has been steadily optimized to meet the demands of a busy clinical laboratory. SelectScience® speaks to Mariela Marinova, MD, to find out more. 

8. Microsampling and LC-MS/MS in Pediatric Research: Exclusive Interview with Giuliana Cangemi

Giuliana Cangemi is head of chromatography-mass spectrometry at the Central Laboratory of Analysis, Giannina Gaslini Children’s Hospital in Genoa, Italy. Giuliana is an expert in her field of liquid chromatography-mass spectrometry (LC-MS/MS), and was a speaker at the MSACL 2016 meeting. In this exclusive interview, Giuliana discusses the use of this technology in pediatric testing. 
 

Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS System

Thermo Fisher Scientific

The Thermo Scientific™ Q Exactive™ GC system is the first-ever combination of high resolution gas chromatography with high-resolution/accurate-mass (HR/AM) Orbitrap detection for the most comprehensive sample characterization. This easy-to-use system provides the most comprehensive characterization of samples in a single analysis for the highest confidence in compound discovery, identification, and quantitation. Building upon the flexible modularity of the Thermo Scientific™ TRACE™ 1300 Series GC, including user-exchangeable injectors and detectors, the Q Exactive GC system has the quantitative power of a GC triple quadrupole MS combined with the high precision, full scan high-resolution/accurate-mass capability that only Orbitrap technology can offer.   Key Features: Advanced quadrupole technology (AQT) for high transmission of selected masses Resolving power up to 120,000 at m/z 200 Part-per-trillion-level sensitivity Thermo Scientific™ Extractabrite™ ion source for robust, rugged electron impact (EI) and chemical ionization (CI) performance Curved linear C-trap for precise ion injection HCD collision cell for higher energy collisional dissociation provides MS/MS ion characterization Intelligent identification software elucidates the nature of each injected sample. Applications: Untargeted and targeted metabolomics Food and beverage Industrial analyses Environmental Pharmaceutical Clinical and toxicology

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