Application Note: Use of X500R QTOF for Monitoring Unexpected Additives in Nutritional Supplements
12 June 2017

SCIEX’s X500R QTOF high resolution mass spectrometry system can be used for rapid monitoring of additives in nutritional supplements; after sample injection, a first order mass accuracy number and second order fragmentation spectrum are simultaneously obtained. Currently, over 50 additives can quickly be qualitatively confirmed in this way. Matrix interference in complex matrices can be overcome for specific screening of additives; preprocessing is even simpler and more convenient. The new SCIEX OS software fully integrates instrument control, data collection, data handling, and other processes. The workflow is more intuitive and smarter; this method provides an efficient means for rapid, high-throughput monitoring of nutritional supplements for additives.