Application Note: Transfer of an SEC Method for Monoclonal Antibody Analysis from HPLC to UHPLC Using the ACQUITY Arc System
2 November 2015

This application used a monoclonal antibody to assess Size Exclusion Chromatography (SEC) method transfer from an Agilent 1100 Series instruments to the ACQUITY Arc System. SEC is a common technique used in the pharmaceutical industry for the analysis of biotherapeutics, including monoclonal antibodies. SEC is often used through the lifecycle of a drug product, from discovery through commercialization.