The Power of High Resolution Accurate Mass Using Orbitrap Based GC-MS
The Power of High Resolution Accurate Mass Using Orbitrap Based GC-MS
14 Jun 2016Obtaining mass spectrometer (MS) measurements with high mass accuracy is essential to providing the required selectivity in complex matrices and to increasing the confidence in compound identification and confirmation. For the former, obtaining a consistently high mass accuracy allows the use of very narrow mass extraction windows, taking full advantage of the instrument’s mass resolving power. For the latter, measuring the mass of a chemical with sufficient accuracy allows the chemist to predict the elemental composition and isotopic ratios to help identify the chemical structure of the substance. This application note demonstrates that, using the high resolution of the Q Exactive GC mass spectrometer, excellent mass accuracy is always available to the user, across a wide concentration range and in the presence of a complex chemical background.
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Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS System
Thermo Fisher ScientificThe Thermo Scientific™ Q Exactive™ GC system is the first-ever combination of high resolution gas chromatography with high-resolution/accurate-mass (HR/AM) Orbitrap detection for the most comprehensive sample characterization. This easy-to-use system provides the most comprehensive characterization of samples in a single analysis for the highest confidence in compound discovery, identification, and quantitation. Building upon the flexible modularity of the Thermo Scientific™ TRACE™ 1300 Series GC, including user-exchangeable injectors and detectors, the Q Exactive GC system has the quantitative power of a GC triple quadrupole MS combined with the high precision, full scan high-resolution/accurate-mass capability that only Orbitrap technology can offer. Key Features: Advanced quadrupole technology (AQT) for high transmission of selected masses Resolving power up to 120,000 at m/z 200 Part-per-trillion-level sensitivity Thermo Scientific™ Extractabrite™ ion source for robust, rugged electron impact (EI) and chemical ionization (CI) performance Curved linear C-trap for precise ion injection HCD collision cell for higher energy collisional dissociation provides MS/MS ion characterization Intelligent identification software elucidates the nature of each injected sample. Applications: Untargeted and targeted metabolomics Food and beverage Industrial analyses Environmental Pharmaceutical Clinical and toxicology