The Development of a Sensitive Multi-Residue LC-MS/MS Method for the Quantitative Determination of Mycotoxins in Animal Feedstuffs and Silage Using Xevo TQ-S

11 May 2014

In this application note, Waters reports the development of a quantitative method for the determination of 33 relevant mycotoxins in a variety of animal feed and silage extracts. The ACQUITY UPLC I-Class System coupled to a Xevo TQ-S was used for rapid, high quality, and ultra-sensitive analysis of multiple mycotoxins in feed extract. The goal of this application note was to investigate the effect of matrix dilution and enhanced instrument sensitivity to overcome common analytical challenges such as ion suppression and to reduce the effects of matrix variability.

Xevo TQ-S

Waters

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated method development for sensitive and robust methods. Reducing complexity, increasing ease of use, and ensuring the correct result every time.

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The Development of a Sensitive Multi-Residue LC-MS/MS Method for the Quantitative Determination of Mycotoxins in Animal Feedstuffs and Silage Using Xevo TQ-S