Application Note: Pathway-Targeted Metabolomic Analysis in Oral/Head and Neck Cancer Cells Using Ion Chromatography-Mass Spectrometry
2 February 2015

In this work, a high flow rate ion chromatography coupling with high-resolution, accurate-mass MS was utilized for targeted analysis of the TCA cycle intermediates to shorten the run time and increase throughput and robustness to accommodate the hundreds of samples typically analyzed in a targeted metabolomics project.