Application Note: nanoDSF Thermal Unfolding Analysis of a Membrane-bound Esterase in Various Detergents
12 July 2016

This application note describes a study in which the Prometheus NT.48 was used to determine the thermal stability of the membrane esterase PA2949 from Pseudomonas aeruginosa in presence of various detergents. The detergent type strongly affected enzyme thermal stability, which moreover correlated with enzyme activity.