High throughput screening of cardiac ion channels

18 Aug 2020

Here Nanion Technologies GmbH, presents high-quality data with reliable pharmacology on hERG expressing CHO cells, NaV1.5, CaV1.2 or KvLQT1 expressed in HEK293 cells and Kir2.1 expressed in RBL cells on the SyncroPatch 384PE or Patchliner. Additionally, electrophysiological recordings on the Patchliner and Impedance measurements on the CardioExcyte 96 of stem cell-derived cardiomyocytes are shown.

SyncroPatch 384

Nanion Technologies GmbH

The SyncroPatch 384 is a revolutionary automated patch clamp system combining high quality electrophysiological data acquisition and analysis with state-of-the-art liquid handling. With 384 amplifier channels and a 384-pipetting head, up to 384 cells can be recorded in parallel, resulting in a throughput of up to 20,000 high-quality data points per day. 

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Patchliner

Nanion Technologies GmbH

The Patchliner is a fully automated patch clamp system which records from either 4 or 8 cells simultaneously. The HEKA EPC10 amplifiers, full control over the pipette speed, ability to change protocols on-the-fly and flexible add-ons for temperature control and dynamic clamp make this instrument the most versatile APC system on the market. 

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High throughput screening of cardiac ion channels