Application Note: High-Throughput Imaging Assays Using Zebrafish, a Model Organism for Human Disease
13 February 2019
Recently, zebrafish-based screening has gained favor as an alternative to mammalian screening due to cost, throughput and reduced ethical concerns. Zebrafish are a useful model for drug development because of their high biological similarity to humans. Studies in ontogeny and organogenesis have shown that their primary organ systems are very similar to humans, and the synteny between zebrafish and Homo sapiens is as high as 70-80%.