Application Note: Extraction of 11-nor-9-carboxy-Δ9-tetrahydrocannanbinol from Urine Using ISOLUTE® SLE+
9 July 2012

This application note describes the extraction of THC and metabolites from urine using ISOLUTE SLE+ columns or plates. Globally, cannabis is one of the most widely used illicit drugs. The naturally occurring cannabinoids found in hemp species bind to receptors in the brain and cause sensations of relaxation and calm. Widespread legislation against the use of cannabis has led to the necessity for rapid and reliable methods for the analysis and quantitation of cannabinoids and metabolites. The most prevalent marker in biological samples taken from cannabis abusers is 11-nor-9-carboxy-Δ9-THC. This study demonstrates a supported liquid extraction procedure for 11-nor-9-carboxy-Δ9-THC.