Application Note: Development of a High Sensitivity SPE-LC-MS/MS Assay for the Quantification of Glucagon in Human Plasma Using the ionKey/MS System
26 June 2014

This application note demonstrates that the combination of ionKey/MS, mixed-mode μElution SPE, and higher m/z b or y ion MS fragments provides a selective and sensitive method for the accurate quantification of low pg/mL concentrations of glucagon in extracted plasma.