Application Note: Analysis of Pharmaceuticals and Pesticides in Bottled, Tap, and Surface Water Using ACQUITY UPLC Systems with 2D-LC Technology
12 November 2014

This application demonstrated the disruptive nature of ACQUITY UPLC Systems with 2D-LC Technology with a Xevo TQD Mass Spectrometer. The application targeted the analysis of PPCP’s and pesticides in bottled, tap, and surface water. The limit of detection in this study was 1.0 ppt with a 10:1 enrichment from the extraction protocol (15 min total) and a 200:1 enrichment from the at-column dilution option, for a total of 2000:1. The recovery data for bottled, tap, and surface water samples using a micro extraction protocol shows comparable results to application with macro extraction protocols.