Application Note: VERTEX FM Wide Range FIR-MIR Spectroscopy: Added Value for the Differentiation of Polymorphs
20 November 2018
Spectroscopic techniques have a great potential for analyzing polymorphic forms and are used more and more frequently for this kind of analysis. Especially IR and Raman spectroscopy offer fast and efficient identification and quantification capabilities. Mid IR spectroscopy, where fundamental molecular vibrations are excited, is a routine method in the Pharmacopoeias for the testing of the chemical identity. But far IR spectroscopy, where back bone vibrations of larger molecules or intermolecular vibrations in crystal lattices are excited, is widely applied to the identification of polymorphic forms and solvates. The new VERTEX FM functionality offers the measurement of the complete FIR-MIR spectral range in one step and allows for simultaneous identification and polymorph screening of samples.