ResourceLife Sciences
TRPA1 Activation by Allyl Isothiocyanate
8 Feb 2011This application note presents data recorded on the Port-a- Patch® with external perfusion showing recordings of human TRPA1 (hTRPA1) activated by increasing concentrations of allyl isothiocyanate (AITC). hTRPA1 could be repetitively stimulated using low concentrations of AITC but was desensitized by high concentrations of AITC (>10 μM).
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Port-a-Patch
Nanion Technologies GmbHThe Port-a-Patch is a miniaturized semi-automated patch clamp system supporting giga-seal recordings from one cell at a time. It offers fast and easy access to patch clamp data with only minimal training. Not only a powerful research tool but also ideal for educational purposes and quick tests of cells and ion channels.