Application Note: Targeting natural killer cell activity with humanized NSG-IL15 mouse model
15 March 2021

In this application note, The Jackson Laboratory demonstrate how the cord blood CD34+ hematopoietic stem cell (HSC) humanized NSG™-IL15 mouse enables in vivo efficacy research for compounds targeting human natural killer (NK) cell activity including antibody-dependent cellular cytotoxicity (ADCC).