Application Note: Size Exclusion analysis following IdeS digestion using a Biozen™ dSEC-2 Column
30 June 2022

In this application note, Phenomenex demonstrates the analysis of antibodies using enzymatic digestion. Specifically, Phenomenex uses the cysteine protease IdeS, which cleaves IgGs below the hinge region and yields a Fab’2 & two Fc/2 fragments.