Application Note: Rapid Evaluation of Compound Allergenicity by Measuring Histamine Release on Stimulated Whole Blood
5 December 2018

This study demonstrates the capability of the HTRF Histamine-Dynamic kit to measure histamine release in whole blood samples treated with different allergen mixes. Investigating histamine release in fresh blood enables a rapid assessment of immunogenicity reactions and thus aids in efficiently predicting the safety of drug candidates.