Application Note: QCI Interpret Translational whole-exome sequencing workflow
1 April 2024

Whole-exome sequencing (WES) aids in identifying novel gene-disease associations and addressing phenotypic variability by uncovering the genetic basis of multiple diagnoses in a single patient. Despite significant contributions from other genetic analysis methods, such as genome-wide association studies and candidate gene mutation screening, a substantial portion of hereditary cancer cases still lack a known genetic mechanism. In this application note, QIAGEN presents QCI Interpret Translational, a comprehensive software solution, which streamlines variant annotation, filtering, and prioritization processes, enabling researchers to identify clinically relevant variants accurately and efficiently.