Application Note: Multiplex analysis of Predictive Oncology's 3D tumor models using Tecan's Spark Cyto imaging multimode reader
19 February 2024

In this application note, Tecan highlights the use of its Spark® Cyto reader as a powerful instrument for analyzing 3D cell cultures in drug development and cancer research. The organ-specific extracellular matrix developed by Predictive Oncology is utilized to enable in vivo representative testing, which leads to improved accuracy in predicting a tumor's response to drugs, optimization of candidate screening, enhanced evaluation of off-target toxicity, and biomarker discovery. The note includes four independent studies that demonstrate the Spark Cyto reader's suitability for high-throughput 3D cell culture studies, delivering maximum data output and information content.