Miniaturized Drug Sensitivity and Resistance Testing with the Echo® Liquid Handler and Access™ Workstation
17 Jan 2014Recently identified associations between variants of cancer genes and drug resistance increase the value for comprehensive drug sensitivity and resistance testing in combination with molecular profiling of cancer cells. This application note discusses the implementation of miniaturized drug sensitivity and resistance testing, at the Institute of Molecular Medicine in Finland (FIMM), with assay-ready plates produced by the Echo liquid handler.
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Echo® 650 Acoustic Liquid Handler
Beckman Coulter Life SciencesEnables assay miniaturization in a broad range of applications. Transfer from 384-well and 1536-well microplates. Accurate, precise, contact-free acoustic transfer in volumes as low as 2.5 nL Transfer from Echo Qualified sample tubes* and microplates.
Access™ Laboratory Workstation
Small-Scale Automation with Large-Scale Results Access™ laboratory workstations multiply the benefits of the Echo® liquid handler by improving overall assay throughput and reproducibility. With the ability to integrate a variety of devices and the modularity to scale when needed, each workstation offers the flexibility required by frequently-changing assay requirements. All Access workstations are optimized at install and include all safety mechanisms required for CE compliance. Access workstations use Labcyte Tempo™ automation control software to manage the system configuration and schedule automated routines. Protocols created from Echo® software applications can be imported into Tempo™ software and quickly converted into fully automated routines. Support for a Range of Applications Assay ready plate preparation Lead optimization and secondary screening assays High-throughput gene expression assays Automated protein crystallography setup