Application Note: HPLC method to differentiate four THC stereoisomers formed from Δ9-THC degradation
30 July 2021

Degradation of Δ9-THC to Δ10-THC and Δ6a,10a-THC isomers, provides a challenging separation in cannabis-derived products. In this application note, learn how the use of an immobilized cellulose chiral column under normal-phase liquid chromatography conditions provides an analytical method to fully separate these four THC isomers for identification and accurate determination of potency.