Application Note: Generating Reliable Kinetic Data for Protein-Ligand Interactions
13 November 2017
The community Structure Activity Resource (cSAR) group is developing a database of high quality protein-ligand structures and the corresponding binding affinities. the data will be provided from in-house experiments and community collaborations. the proteins are generally well-studied structures that have been targeted in drug discovery projects. This application note describes how the octet RED96 system has dramatically increased the data that can be produced in a short time, turning it into the workhorse of the cSAR project.