Application Note: Eppendorf solution for MALDI-TOF analyses
19 July 2023

In this application note, Eppendorf highlights the importance of considering leachables in MALDI-TOF analyses using pipette tips made of polypropylene. These leachables, such as biocides and plasticizers, can significantly impact results without users being aware of it. Leachables may produce abnormal peaks or overlay the actual signal, and evidence suggests a cumulative effect occurs with pipette tips. Eppendorf emphasizes the need for liquid handling systems with chemical-resistant materials to ensure analysis accuracy and recommends tips free from dispensable additives. It also offers various liquid handling products with advanced chemical resistance and solutions to prevent contamination and enhance decontamination processes for successful MALDI-TOF analyses.