Application Note: Dissolved oxygen control proportional–integral–derivative (PID) tuning for cell culture applications
27 September 2022

This application note introduces a method developed to optimize the PI values on Eppendorf bioprocess controllers. The method is based on pre-programmed delivery of chemical oxygen scavengers to accurately simulate the oxygen demand throughout a bioreactor cell culture process. This chemical simulation allows for quick and accurate tuning of PI values for cell culture dissolved oxygen control.