Application Note: Cerenkov Imaging of Radioisotopes in IVIS Systems
20 May 2014

Optical imaging detects photons in the visible range of the electromagnetic spectrum. PET and SPECT imaging instruments are sensitive to photons in the much higher energy range of x-rays and gamma rays. While the PET and SPECT probes which can generate Cerenkov light in tissue will continue to produce the relevant gamma- and x-rays, visible photons will be produced from the Cerenkov emission, which the IVIS® will detect.