Application Note: Use of impurities in the development and validation of a LC method with CAD detection
23 August 2023
New manufacturing processes, more complicated formulations, and increasingly complex global supply chains are just some of the factors making it more difficult for companies to assess and control for impurities in drug substances and drug products. In this application note from USP, explore the use of impurity samples – such as pharmaceutical analytical impurities (PAIs) – in the development and validation of a liquid chromatography method. Discover how this new method utilizes a charged aerosol detector (CAD), which is suitable for organic impurities testing for Tobramycin, an aminoglycoside antibiotic.