Application Note: Streamlining affinity analysis for accelerated lead screening, characterization, optimization and final selection
24 February 2021
A critical stage in biologics drug discovery and development is the selection and characterization of lead molecules from large libraries. These molecules need to be screened for binding specificity and functional activity. A screening criteria for such molecules is their affinity for the target, thereby warranting the need for analytical instruments capable of characterizing such molecules. The Octet® RED96e system is equipped with features that enable such characterization of a diverse range of biological molecules, including those that may be temperature sensitive. In this white paper, Sartorius detail features and capabilities of the Octet® RED96e system for streamlining affinity analysis for rapid lead molecule screening.