Application Note: Enhancing the LC-MS/MS analysis of B group vitamins with MaxPeak High Performance Surface technology
19 February 2021

In this application note, Waters highlights the improvements seen when applying HPS technologies to the analysis of B-group vitamins by liquid chromatography, coupled with tandem quadrupole mass spectrometry (LCMS/MS). The ACQUITY PREMIER System and ACQUITY PREMIER BEH C18 Column promise to show performance enhancements when compared to a conventional system and column. Waters observed better peak shapes, increased response, higher sensitivity, and no analyte carry-over using the HPS technologies.

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