Application Note: Comprehensive characterization of an antibody-drug conjugate using electron activated dissociation
27 September 2023
In this application note from SCIEX, explore an in-depth characterization of a lysine-linked antibody-drug conjugate (ADC) using a streamlined, electron-activated dissociation (EAD)-based peptide mapping workflow in a single injection. This workflow combines the capabilities of EAD for peptide mapping with automated data interpretation offered by Biologics Explorer software. The workflow provides confident ADC sequence confirmation and accurate localization of the payload.