Developing Effective Assays with Clever New Assistance Software

Learn how the team at NanoTemper Technologies is helping scientists design better assays and quickly generate meaningful results

29 Mar 2017
Lucy Vass
Administrator / Office Personnel

Editorial article

Julia Sica, Guest Editor

Beate Kern, Customer Support NanoTemper Technologies

Have you ever been stuck in your experiment because of trouble with the technologies you use? Not sure how to interpret the output? At NanoTemper Technologies, Beate Kern is part of Customer Support and happy to help you out. In this interview with Guest Editor Julia Sica, she talks about the experiences that brought her to this field of work, her role in developing clever assistance software and the recent introduction of webinars.

JS: What is your scientific background and how did you find your way to NanoTemper Technologies?

BK: I studied biology with focus on microbiology in Munich, except for a year abroad in Japan during my Master's degree. The topic of my PhD thesis was investigating the consequences of the toxins of Helicobacter pylori on human T cells - so it had nothing to do with the aspects we work with at NanoTemper Technologies (such as proteins or affinities) at all! Close to the end of my PhD, I started working part-time at the Deutsche Museum, Munich, a huge museum for science and technology, where I explained basic methods like PCR or DNA extraction to pupils. I really enjoyed teaching and therefore I was looking for a job where I could combine my scientific background with teaching and training tasks.

JS: What are your main tasks right now in Customer Support?

BK: Basically, I am helping our customers be successful in their research. This involves training new users who don't have any experience with our technology, but I also assist advanced users with their experimental design and data analysis. I support them if they have questions about their application and offer practical advice.

JS: What do you find most exciting about your work?

BK: I really appreciate the contact with different scientists and helping them to achieve their goals. It is great to still be connected to research, working with our clients on diverse topics. The samples are always different, their approaches vary and it is exciting to support various projects and to solve some of their problems.

JS: What are the biggest challenges you face?


We want to make the whole process of using our instruments easier for our clients.

Beate Kern  NanoTemper Technologies


BK: In the last two years at NanoTemper Technologies, I've been visiting many clients in Europe. I noticed that some customers are faster at learning new software than others and if we make our instruments as easy as possible to use, then they can focus their energy on their research.

JS: What exactly is the goal of your assay development software?

BK: We want to make the whole process of using our instruments easier for our clients. Our new MO.Control software takes them by the hand and leads them through the procedure step by step on their way to the results. It also runs some important pre-tests, performs quality checks and helps the clients understand the outcomes and data. Since our tools are becoming a standard technology for the pharmaceutical industry, it is important to make them as easy to use as possible.

Watch this video to find out more about the features of the MO.Control software

JS: What was your motivation to help develop the software?

BK: The bulk of the work was done by our brilliant team of software developers and designers. Since I am clearly not a software developer, my role is to contribute to the software from the client's perspective. Supporting our customers taught me which kinds of experiments they typically perform and which problems they face. Since I also took part in writing the current manuals and FAQs, I am aware of how a new user feels and I can clearly explain all the procedures.

JS: What is your impact on the new software?

BK: I was mainly helping to design MO.Control software by making the software development team aware of customer needs. For example, I kept them updated with typical problems that occur in assay development so they could help to solve them. Moreover, I have written entries to an in-software database we call NanoPedia to facilitate the support.

JS: NanoTemper Technologies now also offers support webinars. What are the reasons and the goals?

BK: We are, of course, adding additional resources to guide and support everyone who uses our products. We realized that additional users may come on board after we've provided the initial training so this helps those who may have missed it. It would be great to increase the contact with our customers and offer help on different levels. Therefore, we started to offer webinars on different specific topics - our first one was about Assay Setup for MicroScale Thermophoresis. Since we received such positive feedback, we're continuing our efforts with an introduction to the new MO.Control software and how it guides you through MicroScale Thermophoresis experiments. We are planning to offer more webinars in the future, so please visit our website to stay informed about upcoming webinars, it would be great to meet you there!

Learn more about the new MO.Control Software from NanoTemper Technologies.

Have you used a NanoTemper product? Write a review today for your chance to win a $400 Amazon Voucher or an iPad Air®.

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Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.Software SolutionTraining SoftwareProtein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.