NanoTemper Technologies GmbH develops, produces and markets innovative, high quality instruments for biomedical research. The products are based on NanoTemper’s unique and proprietary technology termed MicroScale Thermophoresis (MST).
The company was founded as a spin off from the Center for Nanoscience (CeNS) at the University of Munich (LMU) in 2008. After a hugely successful introduction of the Monolith NT.115 in 2010, NanoTemper introduced a new instrument, the Monolith NT.LabelFree, in December 2011. The company, with headquarters in Munich, Germany, is rapidly expanding globally. NanoTemper instruments are used by hundreds of scientists on numerous continents. Recently, NanoTemper has received several prizes including the German Innovation award, the Step Award for outstanding development of the company, and the Red Dot Design Award “Best of the Best” for the Monolith NT.115 instrument.
The MST-technology was developed at the Biophysics Department at the University Munich. MST allows fast, immobilization-free and label-free quantification of biomolecular interactions with high sensitivity and accuracy as well as low sample consumption. The term MicroScale Thermophoresis describes the directed movement of molecules along a microscopic temperature gradient. The thermophoretic movement is dependent on the size, charge and hydration shell of molecules. It allows for the measurement all kinds of biomolecular interactions ranging from protein-ion, protein-compound/fragment to protein-macromolecular complex interactions (e.g. ribosomes and liposomes). Worldwide, NanoTemper is the only provider of this patented technology, which has major advantages over existing technologies and significantly augments current academic and biopharmaceutical research workflows.