Transcreener® GDP GTPase Assays by BellBrook Labs

Manufacturer BellBrook Labs  |  Available Worldwide
BellBrook Labs Transcreener® GDP GTPase Assays


Transcreener® GDP GTPase Assays by BellBrook Labs product image
Transcreener® GDP GTPase Assays
Request Pricing

Receive your quote directly from the manufacturer.



0 Scientists have reviewed this product


Write the First Review

No Reviews

The Bell Brook Labs Transcreener® GDP Assays are single step, homogenous, fluorescent assays for direct detection and screening of GTPases.

Available with fluorescence polarization (FP) and fluorescence intensity (FI) readouts, they provide a safe, HTS-compatible alternative to cumbersome radioassay methods and are more sensitive and less subject to interference than colorimetric phosphate detection methods. Based on BellBrook's proprietary nucleotide immmunodetection technology, the BellBrook Transcreener® GDP Assays are compatible with any enzyme class that produces GDP, including monomeric small G proteins, such as CDC42, and Gα subunits of heterotrimeric G proteins, such as Gαi1.


Features of BellBrook Labs Transcreener® GDP Assays:

  • SENSITIVE: Highly selective, high affinity antibody means you can detect nanomolar GDP in the presence of 100-fold excess GTP
  • UNIVERSAL: Use with any GDP-producing enzyme, at initial GTP concentrations of 0.1 to 1,000 μM.
  • TURNKEY PROTOCOL: Run your enzyme reaction, add Transcreener detection reagents, read your plates.
  • TWO DETECTION OPTIONS: Available in Fluorescence Polarization (FP) and Fluorescence Intensity (FI) detection modes that have been validated with major instrument platforms.
  • VALIDATED HTS PLATFORM: Based on the Transcreener ADP2 Assay, which has been validated in over 40,000,000 wells of pharma HTS. See peer reviewed publications