Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
Powerful auto-range pathlength technology facilitates accurate measurements for concentrated samples with no need for dilutions
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Essential instrument to any sequencing lab.
Analyse purity of DNA and RNA extractions
Easy to use and helps us ensure samples are clean enough for further processing. No extra consumables needed, except tips, which makes it a long term, environmentally friendly system.
Review Date: 15 Apr 2024 | Thermo Fisher Scientific
Very good results
RNA, DNA and proteins quantification
Very easy to use and obtained results within few minutes. Accurate quantification intruments specially when quintify small concentration in the sample.
Review Date: 14 Apr 2023 | Thermo Fisher Scientific
It's an absolute necessity for our laboratory.
Quantify nucleic acids
It's easy to turn on and the software let's me export data directly to an Excel file. Data is reproducible.
Review Date: 13 Jan 2023 | Thermo Fisher Scientific
Time and material saving
Spectrophotometer
Very low volume needed to measure, correct and fast measurements
Review Date: 14 Nov 2022 | Thermo Fisher Scientific
Easy to use and reliable
DNA concentration measurement
Easy to use and reliable
Review Date: 31 Oct 2022 | Thermo Fisher Scientific
Whether it be transfection or cloning I can always rely on my NanoDrop
Nucleic Acid qualitative and quantitative assessment
I would say I never felt the need of any update, the results I get from my NanoDrop are always promising and useful.
Review Date: 30 Jul 2022 | Thermo Fisher Scientific
Love the instrument, wish it came with manuals
Protein concentration gauge
Great results, pretty consistent, the only issue is that I wish it came with manuals that explained exactly how the calculations worked for the path length/concentration measurements.
Review Date: 15 Jul 2022 | Thermo Fisher Scientific
Great results in little time, we don't know what we would do without it!
Nucleic acid analysis
The Nanodrop has saved us lots of time and sample volume. It is very easy to use and the results are highly reproducible as compared to our large volume UV-VIS spectrophotometer. The nanodrop takes up very little space and is low maintenance. We love this little piece of valuable equipment!
Review Date: 8 Jul 2022 | Thermo Fisher Scientific
Very effective, efficient and gives satisfactory results
Spectrophotometry
Very effective and efficient in spectrophotometric analysis
Review Date: 28 Jun 2022 | Thermo Fisher Scientific
necessary in any lab
quantification of nucleic acids
Easy to use, no reagents needed, reproducible results
Review Date: 27 May 2022 | Thermo Fisher Scientific
The NanoDrop One/NanoDrop OneC spectrophotometers feature an ergonomic, standalone design with integrated Android tablet, eliminating the need for a separate computer and providing seamless data transfer via Wireless (if available), Ethernet or USB. Multi-sample processing is streamlined with Auto-Measure and Auto-Blank functions. bBecause of its wider dynamic range using auto-range pathlength technology, no dilutions are necessary for highly concentrated samples. The Acclaro technology enhances user understanding of sample quality while delivering accurate quantitative measurements.
- Wide spectral range (190-850 nm) for measuring a variety of samples types
- Combining the proprietary sample-retention system with cuvette capability accommodates low and high concentrations
- Pedestal measurements that require only 1 – 2 µL of your sample and do not require sample -dilution, even for highly concentrated samples
- Calculates sample purity ratios (A260/A280 nm and A260/A230 nm)
- Pre-configured methods for DNA, Protein A280, Microarray, Protein and Labels, Pierce 660, Bradford, BCA, and Lowry
- User-friendly software includes custom methods and data export capabilities
Brochures
Gain next-level precision with microvolume spectrophotometry and fluorescence
The Thermo Scientific™ NanoDrop™ Ultra family builds on two decades of innovation in microvolume UV-Vis spectrophotometry. Designed to provide researchers with accurate and reproducible results, these instruments combine absorbance and fluorescence measurements to support a wide range of nucleic acid and protein quantification applications.
Key features and capabilities:
- Dual measurement modes – Measure highly concentrated samples using absorbance or detect low-concentration samples with fluorescence, all on a single platform
- Acclaro™ sample intelligence technology – Identifies common contaminants such as proteins, phenol, and guanidine salts, providing corrected concentration values and purity insights
- qPCR sample preparation support – Built-in calculators assist in reaction setup, reducing manual calculations and potential errors
- Data integrity and compliance – Optional 21 CFR Part 11 software enables secure data tracking and integration with LIMS and cloud storage solutions
- Broad dynamic range – Absorbance measurements up to 27,500 ng/µL dsDNA and fluorescence detection as low as 0.1 ng/µL, providing flexibility for various sample types
By combining advanced analytical tools with user-friendly software, NanoDrop Ultra instruments are designed to simplify workflows and enhance the accuracy of microvolume quantification. Download the brochure to find out more.
The best tools for DNA and RNA quantification
Nucleic acid quantification (NAQ) determines the concentration of DNA or RNA in a sample, enabling the calculation of the correct amount of nucleic acid required for downstream applications. Using the correct amount of nucleic acid saves time and money, preventing downstream experimental failures, and ensures data quality. Discover how to select the most suitable technology for optimal nucleic acid input, and explore how solutions from Thermo Fisher Scientific offer reliable experimental outcomes, and can help to avoid issues like insufficient amplification or poor sequencing results.
Gold nanoparticle and gold nanoshell analysis
In this eBook, Thermo Fisher Scientific demonstrates the reliability of the NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer in measuring gold nanoparticle and nanoshell concentrations. Gold nanoparticles and nanoshells are becoming increasingly popular as delivery vehicles for various gene therapies, and thus research involving them is of growing importance. The quantification of gold nanoparticle and nanoshell concentrations requires high accuracy and the high cost of the product provides incentive to minimize the sample volumes.
Next-generation sequencing sample preparation with the NanoDrop One spectrophotometer
In this application note, Thermo Fisher Scientific demonstrates the accuracy of the NanoDrop™ One/OneC spectrophotometer in quantifying and qualifying DNA isolated from saliva for downstream next-generation sequencing (NGS). NGS technology provides a genomic analysis to associate diseases such as cancer, heart disease, and diabetes with nucleic acid sequence aberrations. NGS can detect translocations, copy number variants (CNVs), insertions and deletions (indels), and single nucleotide variants (SNVs) with high sensitivity, all of which play a role in disease development. Saliva is a common sample type for genomics research as it provides a painless, inexpensive collection procedure.
Detection of RNA contamination in mammalian DNA preparations
Quantification of nucleic acids has traditionally been performed by determining the UV absorbance at 3 analytical wavelengths: 230 nm, 260 nm, and 280 nm. The information derived from these absorbance measurements allows scientists to measure nucleic acid concentration and to have an indication of sample purity. A disadvantage of this approach is the lack of specificity. Thus, any contaminant that absorbs at these wavelengths will lead to inaccuracies in a nucleic acid concentration result. In this application note, Thermo Fisher Scientific show how a newly introduced feature in Acclaro software allows users to detect and correct for RNA contamination in DNA preparations or DNA contamination in RNA preparations.
Nucleic acid and biotechnology workflow solutions
In this application note, discover products from Fisher Scientific to support your nucleic acid and viral research, as well as vaccine development. The Fisher Scientific channel offers an innovative product portfolio to empower and accelerate every step of your workflow.
Qualification of nucleic acid samples for infectious disease research workflows
Reliable assays are a necessity for timely processing of samples that must be tested for SARS-CoV-2. To improve the quality and reliability of viral detection by the reverse transcription quantitative PCR (RT-qPCR) method, it is important to mitigate potential delays along the workflow. The Thermo Scientific™ Acclaro™ Sample Intelligence technology built in to the Thermo Scientific™ NanoDrop™ One Microvolume UV-Vis Spectrophotometer offers a set of tools that help provide accurate nucleic acid concentrations, identify many contaminants, and help prevent failed experiments.
NGS success: Next-generation sequencing sample preparation with the NanoDrop One spectrophotometer
Achieving accurate sequencing results requires a reliable nucleic acid quantity and purity assessment. Currently, qPCR serves as the gold standard quantification method but is expensive, time consuming, often requires vetting SOPs, and does not provide purity details. As a convenient alternative to qPCR, the Thermo Scientific™ NanoDrop™ One/OneC spectrophotometer provides a sensitive quantification measurement and identifies common nucleic acid contaminants that prevent sequencing success.
This webinar will provide an overview of the NanoDrop One/OneC spectrophotometer as an easier and cheaper alternative to qPCR for ensuring high-quality sequencing data.
Key learning objectives
- Understand and review the NGS workflow
- Learn how to set up your sequencing experiments for success
- Explore the NanoDrop One/OneC Spectrophotometer as an alternative to qPCR quantification
Who should attend?
- Forensic scientists
- Genetic scientists
- Microbiologists
- Molecular biologists
- Pharma/biopharma researchers
- Biomedical researchers
- Principle investigators
- Laboratory Technicians/Technologists
- Agricultural geneticists
- Scientists interested in improving the success rate of NGS with convenient, accurate, cost-efficient tools
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
NGS success: Next-generation sequencing sample preparation with the NanoDrop One spectrophotometer
Achieving accurate sequencing results requires a reliable nucleic acid quantity and purity assessment. Currently, qPCR serves as the gold standard quantification method but is expensive, time consuming, often requires vetting SOPs, and does not provide purity details. As a convenient alternative to qPCR, the Thermo Scientific™ NanoDrop™ One/OneC spectrophotometer provides a sensitive quantification measurement and identifies common nucleic acid contaminants that prevent sequencing success. This webinar will provide an overview of the NanoDrop One/OneC spectrophotometer as an easier and cheaper alternative to qPCR for ensuring high-quality sequencing data.
Key learning objectives
- Understand and review the NGS workflow
- Learn how to set up your sequencing experiments for success
- Explore the NanoDrop One/OneC Spectrophotometer as an alternative to qPCR quantification
Who should attend?
- Forensic scientists
- Genetic scientists
- Microbiologists
- Molecular biologists
- Pharma/biopharma researchers
- Biomedical researchers
- Principle investigators
- Laboratory Technicians/Technologists
- Agricultural geneticists
- Scientists interested in improving the success rate of NGS with convenient, accurate, cost-efficient tools
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
mRNA vaccine development and manufacturing workflows enabled by UV-Vis spectroscopy
In this video, Thermo Fisher Scientific explores mRNA vaccine development. Watch for insights including methodologies, research areas, production, and how to harness UV-Vis spectroscopy for quality assurance and control.
NanoDrop™ Lite Plus Spectrophotometer – the affordable choice for fast, reliable measurements
Quickly and easily assess sample concentration and purity ratios with the Thermo Scientific™ NanoDrop™ Lite Plus Microvolume Spectrophotometer, the entry-level complement to the full-featured Thermo Scientific™ NanoDrop™ One/OneC and NanoDrop Eight Spectrophotometers. While offering fewer features than premium models, this instrument delivers fast, accurate measurements in an easy-to-use, affordable package.
The NanoDrop Lite Plus Spectrophotometer is a valuable teaching tool and is ideal for quality check measurements in busy research labs as well. Measure purified DNA, RNA, and protein concentration up to 30 Abs and calculate critical A260/A280 and A260/A230 purity ratios using trusted NanoDrop technology.
NanoDrop One Spectrophotometer finds and fixes DNA/RNA contamination
This video walks you through a workflow for measuring nucleic acid samples, then identifying and correcting DNA/RNA contamination with NanoDrop One UV-Vis Spectrophotometers.
Quality assessment using NanoDrop One with Acclaro Software
Patrick Brown, a technical applications specialist at Thermo Fisher Scientific, discusses the importance of quality assurance and control for advanced genomic workflows, and explores how the detection of phenol sample contamination can help you quantify DNA samples more accurately using the next-generation Thermo Scientific™ NanoDrop™ One Microvolume UV-Vis Spectrophotometer.
qPCR template qualification using NanoDrop One and Qubit 4
Patrick Brown, a technical applications specialist at Thermo Fisher Scientific, discusses why quantification is critical in modern genomic workflows and describes the different techniques researchers can use to quantify nucleic acid content effectively.
'How the NanoDrop One’s Smart Features Advance our Drug Screening Research'
Watch this video to learn how research assistant Alyssa Grantham is using the NanoDrop One in a busy drug screening lab, and how its smart features help further her research.
‘Why the NanoDrop One is Vital for our Nucleic Acid Research at Cambridge University’
Watch this video to hear how researcher Robyn Hardisty at the University of Cambridge uses the NanoDrop One, and how the NanoDrop One system has become a vital tool for her work into the chemistry of nucleic acids.
The NanoDrop One UV/Visible Spectrophotometer: Next-Generation Spectral Data
In this video, find out how microvolume sample requirements, intelligent contamination detection software, an interactive touchscreen, and full spectral data make the NanoDrop One part of the next generation in UV/Vis spectrophotometry.
Marine research sails into the future with UV-Vis spectroscopy
Dr. Sarah Kingston, Assistant Professor of Oceanography and Chief Scientist for Marine Biodiversity and Conservation at Sea Education Association, discusses the use of UV-Vis spectroscopy in her research and the future of molecular marine research
Mild vs. severe disease: A dengue prediction test with huge potential
StratifiCare™ CEO explains how his newly developed severe dengue prediction test can accurately predict whether a patient will experience severe dengue, reveals how the test will reduce healthcare burdens, and explores why global warming can impact dengue prevalence
Clinical testing: How reliable and inventory-friendly methods are helping overcome post-pandemic hurdles
Find out how using the right tools can help address the biggest challenges in the world of molecular diagnostics
Chosen by you: The most recent Seal of Quality achievements, showcased at AACC
We reveal the latest products to earn these coveted awards based on exceptional review feedback from scientists around the world
New for NanoDrop: 21 CFR part 11 & distinguishing DNA from RNA: Your questions answered
Watch this on-demand webinar to learn more about new updates of the NanoDrop One platform
Nucleic acid contamination detection: Protect DNA and RNA samples to ensure downstream accuracy
How the NanoDrop One UV-Vis Spectrophotometer is bringing specificity to UV-Vis measurements
New Digital Marketing Awards Recognize Scientific, Technological & Communications Excellence
Party during Neuroscience 2018 celebrates the importance of effective conversation between scientists and manufacturers
The New Thermo Scientific NanoDrop One Spectrophotometer Detects Sample Contamination and Helps Troubleshoot Experiments
The Thermo Scientific™ NanoDrop™ One Microvolume UV-Vis Spectrophotometer was designed to provide scientists with intelligent feedback about nucleic acid and protein samples. Read on, as Dr. Voula Kodoyianni, product manager at Thermo Fisher Scientific, describes its unique features.
Your Questions about DNA/RNA Quantification Answered
Learn about sample contaminant detection, an important step towards nucleic acid quantification
New for NanoDrop: 21 CFR part 11 & distinguishing DNA from RNA
Join us on Thursday, September 24, to learn more about new updates of the NanoDrop One platform
