Status:
ReviewerMember since: 2018
Organization: HJF
Instrument is a fancy paperweight and not user friendly.
Application Area: Biochemistry
"The Instrument did not work as promised, and will hardly pass manufacturers QC kits. No replicable results, hard to use, complicated, and time-consuming maintenance. Parts are not reliable and service takes forever. Very costly service plan and hard to work with."
Status:
Advanced ReviewerMember since: 2013
Organization: Janssen
"Claims to be more sensitive instrument but it looks like it depends on assay to assay. May be some assays are not better than MSD."
The Simoa HD-1 analyzer leverages a unique, low-cost “smart” disc developed by Sony DADC to create high density arrays of 40 femtoliter microwells. Each Simoa Disc contains 24 flow cells, each with an array of 200,000 microwells. Following assay, a suspension of analyte capture beads from each sample is passed through a flow cell and across an array (one array per sample) for signal detection. The microwells are just large enough to contain a single bead, allowing for detection of signal from single molecules of labeled analyte.