Products & ReviewSeparations

Raptor™ ARC-18 LC Columns

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality.

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Reviews

Average Rating 4.7

|10Scientists have reviewed this product

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Great column.

 

Average Rating 5.0

Application Area:

PFAS in bottled water

Great column for my application, good separation, non-bleed.

Review Date: 6 Mar 2020 | Restek Corp.

Great product for cannabinoids analysis.

 

Average Rating 5.0

Application Area:

Cannabinoids

The Raptor ARC-18 column is one of the best columns for cannabinoid analysis. The separation for multiple cannabinoids is so great even by using the isocratic condition. Strongly recommended.

Review Date: 9 Dec 2019 | Restek Corp.

Great customer support and an excellent chromatogram reproducibility!

 

Average Rating 5.0

Application Area:

Cannabinoid assay

The column came in very fast. It has easy to understand instructions. It is nice to see that CofAs are available online, less paper. The separation was top notch. As per the paper Restek published earlier, the chromatogram did not disappoint. All peaks were sharp, nicely separated and a very fast run. Extremely satisfied so far. Unfortunately, we are in the process of renovations, so we can not perform many runs right now. Due to that fact I can not comment of how durable the column is. When I had questions about storage of the column, the customer service representative was very quick to respond with very informative explanations. Overall, pleased with the purchase.

Review Date: 9 Dec 2019 | Restek Corp.

Greate results, good seperation.

 

Average Rating 4.3

Application Area:

Analysis of CBD

Achieved good separation of many different CBD compounds.

Review Date: 21 Nov 2019 | Restek Corp.

Worked straight out of the box

 

Average Rating 4.3

Application Area:

Cannabinoid analysis

I have had a look at a number of columns that could be used in cannabinoid analysis, the Raptor ARC-18 was the first and only column that reproduced the described manufacturers method. Following the manufacturers method this column was able to reproduce the method in our laboratory and has continued to do so.

Review Date: 13 Apr 2019 | Restek Corp.

Good product

 

Average Rating 4.7

Application Area:

Potency analysis in cannabis products

I've found the ARC-18 LC columns are the best column for potency analysis in cannabis products. Similar columns from other manufacturers did not get the same resolution as this column. It is robust and lasts for many injections.

Review Date: 12 Apr 2019 | Restek Corp.

Great instrument, okay service.

 

Average Rating 3.3

Application Area:

Cannabinoid potency testing

This column was not the easiest to get set up. I cannot get my peaks to look anywhere as clean as the website shows. I have asked for advice a few times and nothing has really helped. I will keep doing my own R&D to figure out how to improve my peaks. I also would have figured that I would have gotten a notification when the standard procedure changed and the cannabinoid profile expanded. This is a missed opportunity because there could have easily been an up sale. Additionally, I am a customer that will go out of my way to stay with a company and promote them to other people in my industry if I feel that they go above and beyond to ensure that all my needs are met. For instance, I have definitely pushed several of my colleagues to start going through GenTech because of their superb customer care.

Review Date: 12 Apr 2019 | Restek Corp.

Great product, effective and perfect for our needs.

 

Average Rating 5.0

Application Area:

Analyze cannabinoids in cannabis and hemp products

This product is very effective for our use in separating, identifying and quantifying 9 cannabinoid compounds in a large array of products. We have developed a series of methods using the Restek Raptor ARC-18 columns, starting with the 5um particle size then moving down to the 2.7um particle size. We were even given the 1.8um to demo but did not have enough time for method development so would need to revisit the application. Regardless, it is a great product that is commonly used across the industry with a great reputation for THE column to use for cannabinoid analysis.

Review Date: 30 Jul 2018 | Restek Corp.

Robust.

 

Average Rating 5.0

Application Area:

Hop analysis

The Arc-18 column has acceptable separations but the robustness of the column and the resistance to clogging is outstanding.

Review Date: 27 Jul 2018 | Restek Corp.

I will continue to buy and use Restek columns!

 

Average Rating 5.0

Application Area:

Analytical testing

I cannot work without the Restek Raptor ARC18 column that I use daily for my testing needs. Lifespan is great especially with adding on the guard as an option. It is perfect for what I am testing and I would never go back.

Review Date: 27 Jul 2018 | Restek Corp.

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality.

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

Even after extended use in these low-pH (≤ 2.0) conditions, the sterically protected ARC-18 offers consistent retention, peak shape, and response for charged bases, neutral acids, small polar compounds, and more. For the rapid analysis of large, multiclass assays by LC-MS/MS, the Raptor™ ARC-18 truly is ahead of the curve.

Raptor™ ARC-18 LC Columns Features:

  • Ideal for high-throughput LC-MS/MS applications with minimal sample preparation.
  • Well-balanced retention profile for better detection and integration of large, multiclass analyte lists.
  • Sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality.
  • Part of Restek's Raptor™ LC column line featuring SPP core-shell silica.

Column Details:

  • Chemistry: C18, UPS L1
  • Particle Size: 2.7 µm (SPP core-shell)
  • Pore Size: 90 Å
  • Length: 30, 50, 100, 150 mm
  • ID: 2.1, 3.0, 4.6 mm
Application NoteCannabis Testing

Quantitative LC-UV method for testing CBD in topicals

In this application note, Restek demonstrate a LC-UV analysis method for to quantifying CBD in three different sample types: lotions, balms and creams. The product of this sample preparation method is a clean extract that will ensure instrument uptime and maximize column lifetime while providing fast and reliable quantitation of CBD in these complex matrix samples.



Application NoteSpectroscopy

High-Throughput Analysis of Cannabinoids by LC-UV

As the cannabis market grows, interest in more detailed analysis of cannabinoid profiles is expanding because more comprehensive data can be used for strain identification as well as to ensure more accurate potency testing. More than 100 cannabinoids have been isolated from cannabis to date, and these compounds can interfere with the five most commonly analyzed cannabinoids. Download this guide to discover a LC-UV method for the resolution of 16 cannabinoids for which commercial standards are available.


Application NoteCannabis Testing

Fast, low-solvent analysis of cannabinoids increases lab productivity and decreases solvent costs

In the highly competitive cannabis testing market, labs that can expand services while decreasing costs have a strong advantage. High-demand tests such as potency testing and cannabinoid profiling can be improved by increasing speed, expanding analyte lists, and reducing costs. In this application note, Restek demonstrates a rapid, low-solvent analysis method that aims to fully resolve 19 cannabinoids that only uses 3 mL of accetonitrile per run. Using this method promises more accurate potency results and significantly reduced solvent costs.



Scientific PosterSeparations

The Analysis of Vitamin D Metabolites in Serum/Plasma by LC‐MS/MS

Vitamin D exists in two forms, vitamin D2 and vitamin D3. Each undergoes metabolism to form 25‐hydroxyvitamin D2 and 25‐hydroxyvitamin D3. For accurate determination of vitamin D levels in the blood, it is important to distinguish between these metabolites and to separate them from major matrix interferences. In this method, the RaptorTM ARC‐18 column combines the speed of superficially porous particles (SPP) with the resolution of highly selective USLC® technology to produce a simple and rugged method for the determination of vitamin D metabolites in serum and plasma.


Application NoteEnvironmental

Improved Analysis of Aldehydes and Ketones in Air Samples with Faster, More Accurate Methodology

Accurate analysis of aldehydes and ketones in air samples is an important part of monitoring air pollution and protecting human health around the world. These airborne carbonyls from industrial and vehicle emissions are precursors to ozone in smog and are associated with respiratory and pulmonary problems. The following application note details an improved methodology for this analysis.

Restek Announces New Raptor™ ARC-18 Columns for LC-MS/MS

The new Raptor LC columns are ideal for high-throughput LC-MS/MS applications with minimal sample preparation. Restek developed a well-balanced retention profile for better detection and integration of large, multiclass analyte lists. The columns are sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality. Restek's Raptor™ LC column line also features SPP core-shell silica, providing fast separations without the need for expensive Ultra High Performance Liquid Chromatography (UHPLC) instruments, thereby increasing sample throughput without capital investment. Interview filmed by SelectScience at Pittcon 2014.

Editorial ArticleEnvironmental

Chromatography revolutionizes PFAS analysis and detection

As concerns about PFAS health risks rise, advancements in chromatography are transforming our understanding of these persistent chemicals. Explore how innovative techniques enhance detection and analysis, paving the way for safer environments and better public health.










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