Raptor™ C18 LC Columns (USP L1)
Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.
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Excellent performance!
Environmental, PFAS
The column is very efficient and robust. I mount a column guard and after more than a year of use the peaks have remained the same.
Review Date: 29 Jul 2021 | Restek Corp.
Excellent column, highly recommended
Pharmaceutical
It was highly reliable column, good value for money.
Review Date: 26 Jul 2018 | Restek Corp.
"Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.
Every LC lab has a cache of C18s, but every C18 is not created equal. Because the chemistry tends to be similar, the silica support that carries this ubiquitous octadecylsilane phase becomes vitally important. When you need a general-purpose LC column, don’t just grab any C18. Choose the speed, efficiency, and long-lasting ruggedness of the new Raptor™ C18 SPP LC column.
The traditional end-capped Raptor™ C18 offers the highest hydrophobic retention of any Raptor™ phase, and it is compatible with a wide range of mobile phases from moderately acidic to neutral (pH 2–8). Whether for food safety or environmental or bioanalytical analyses, this new phase offers consistently excellent data quality in less time across myriad reversed-phase applications, matrices, and compound classes.
To lower costs and improve profitability, you need columns to last longer, data to be reproducible, and existing HPLC instrumentation to run faster. Get there with the only general-purpose C18 that gives you Selectivity Accelerated.
Features:
- A traditional end-capped C18 ideal for general-purpose use in reversed-phase chromatography.
- Wide pH range (2–8) provides excellent data quality for many applications, matrices, and compounds.
- Offers the highest hydrophobic retention of any Raptor™ phase.
- Part of Restek’s Raptor™ LC column line featuring 2.7 and 5 μm SPP core-shell silica.
Column Specifications:
- Stationary Phase Category: C18, octadecylsilane (L1)
- Particle Size: 2.7, 5.0 μm
- Pore Size: 90 Å
- Length: 30, 50, 100, 150, 250 mm
- ID: 2.1, 3.0, 4.6 mm
A methods-based reference to lab supplies for PFAS testing
This Restek guide provides a concise overview of lab supplies optimized for PFAS analysis. It highlights the importance of minimizing contamination and analyte loss, and offers method-specific recommendations for equipment like SPE cartridges, vials, columns, and calibration standards across major global testing protocols.
Advanced analytical solutions for PFAS Analysis
This comprehensive guide from Restek provides everything analytical labs need for accurate, efficient, and compliant PFAS testing. Covering certified reference materials (CRMs), LC and GC columns, sample preparation tools, and air/gas sampling equipment, it’s a one-stop resource for labs working with water, food, environmental, and industrial samples. Featuring PFAS 3 and PFAS 4 mixes, method details, and product specifications, this catalog supports both routine and advanced PFAS workflows.
Rapid Analysis of 17 Bile Acids in Human Plasma by LC-MS/MS
Quantitative analysis of bile acids in plasma is critical for diagnosing liver disease as well as assessing drug safety. Accurate reporting can be difficult because of analyte characteristics, matrix effects, and other factors. Here, we establish a rapid, robust, and selective LC-MS/MS method for the analysis of bile acids in human plasma using a Restek Raptor C18 column. One of the significant improvements over other reported methods was the baseline separation of all 17 bile acids in 6 minutes, including three isomer groups.
Improved Analysis of Aldehydes and Ketones in Air Samples with Faster, More Accurate Methodology
Accurate analysis of aldehydes and ketones in air samples is an important part of monitoring air pollution and protecting human health around the world. These airborne carbonyls from industrial and vehicle emissions are precursors to ozone in smog and are associated with respiratory and pulmonary problems. The following application note details an improved methodology for this analysis.
The Effects of LC Particle Choice on Column Performance
Superficially porous particles (commonly referred to as SPP or “core-shell” particles) have proven to provide fast and efficient LC separations. These particles feature a solid, impermeable core enveloped by a thin, porous layer of silica that offers significantly higher efficiency and sensitivity than traditional fully porous particles (FPP). In this application note, performance of Raptor™ 5 μm SPP LC column is compared to traditional 3 and 5 μm FPP LC columns. We will demonstrate how faster, more efficient analyses can be attained with greater sensitivity and reduced system pressure by switching from fully porous particles to superficially porous particles—without changing instrumentation.
PFAS analysis – why a delay column is important
Poly- and perfluoroalkyl substances, or PFAS, are rapidly emerging as some of the most important environmental contaminants to monitor around the world. Their widespread use and environmental persistence make them truly a global issue. Concerns about possible health risks are driving environmental scientists to look for these compounds everywhere. However, one other concerning place where at least some of these compounds are present is inside the very instruments used for PFAS analysis of environmental samples. PFAS delay columns can be used to manage this type of contamination.
Boost sensitivity of metal-sensitive compounds with Restek’s new inert LC columns
New columns are ideal for the analysis of metal-sensitive compounds, including mycotoxins, pesticides, and methylmalonic acid
Three Novel Ways Scientists are Using Chromatography to Keep Environmental Contaminants at Bay
Discover application notes to enhance your environmental testing laboratory output
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