Thermo Scientific™ ProPac® SCX and WCX Protein Column

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Strong and Weak Cation-Exchange Columns for High-Resolution Separation of Proteins and MAbs

The Thermo Scientific ProPac™ SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

ProPac® SCX and WCX Protein Column Features:

  • Characterization and quality control assessment of monoclonal antibodies and other proteins
  • Unequalled resolution
  • High-resolution separations with excellent sample recovery
  • Unmatched column-to-column and lot-to-lot reproducibility
  • Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
  • Highly-efficient peaks with excellent sample recovery
  • Available in different dimensions and formats for flexibility in method development

Column Details:

  • Length: 50, 100, 150, 250 mm
  • ID: 2.0, 4.0, 9.0, 22 mm

Product Overview

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Thermo Scientific™ ProPac® SCX and WCX Protein Column

Manufacturer Thermo Fisher Scientific

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