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Nexera X2 UHPLC by Shimadzu Scientific Instruments Inc.

Manufacturer Shimadzu Scientific Instruments Inc.
4.2
/
5.0
  |  7 reviews
Shimadzu’s Nexera X2 Series delivers superior, real-world performance across a wider application range while delivering unparalleled flexibility and reliability in HPLC/UHPLC analyses. Like its predecessor, the Nexera X2 is optimized to enable analysis at pressures up to 19,000 psi without compromising performance and data quality. Nexera X2 autosamplers provide near-zero carryover, support ultrafast analysis with the world’s fastest cycle time (14 secs), and deliver excellent injection reprodu... Read more


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Nexera X2 UHPLC
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Average Rating: 4.2
7 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
Write your own review


Great results and very good and important
Rating: 5.0

  • Application Area: Determine the amount of active materials in tests

"Very good and important to us in my company It is very easy to use and you can use it to make a wide range of types of tests"

Review date: 23 May 2017 | Nexera X2 UHPLC

  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Endoceutics



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Overall I recommend this instrument for any UHPLC (below 10000 psi) need.
Rating: 4.0

  • Application Area:Pharma, CRO, Biothecnologies

"The UHPLC Shimadzu Nexera really surprised me with its roughness. Being an instrument maintenance specialist, this is very important for me. Chromatography is as good as a Waters UPLC and carry over is absent. If carry over is observed, there is more than enough options to remove it. The new rack changer is working properly since there is no error but it is not very efficient."

Review date: 21 Dec 2016 | Nexera X2 UHPLC

  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Multani Pharmaceuticals Limited (Analytical Divisi



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Once procured and installed, forget other worries to run. Output reproducible, least headache to maintain and train new entrant.
Rating: 4.0

  • Application Area:Drugs, Cosmetics and Food products

"HPLCs manufactured by Shimadzu was best in class. Easy to handle, maintain, Qualification and uses. Value for money."

Review date: 19 Aug 2016 | Nexera X2 UHPLC

  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Santen Pharmaceutical Co., Ltd.



  • Ease of use
    3 out of 5
    After sales service
    2 out of 5
    Value for money
    3 out of 5
This instrument is best solution.
Rating: 2.7

  • Application Area:Bioanalysis

"This instrument has high robustness and high performance. Comparing to other HPLC product, this instrument has low carryover and high-speed motion of sampling needle."

Review date: 12 Jul 2016 | Nexera X2 UHPLC

  • Status:

    Reviewer

  • Member since: 2016

  • Organization: JSS University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Value for money
Rating: 5.0

  • Application Area:Analyze drug content in formulations

"User friendly application. Quality of product is good and suggestible. We achieve reliable and reproducible results in stipulated time. Post purchase service is good."

Review date: 18 Feb 2016 | Nexera X2 UHPLC

  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: Institute of Chemical Technology



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Excellent reproducibility, accurate analysis, real asset to R&D people.
Rating: 4.7

  • Application Area:Analysis of Impurities in Intermediates preparation for specialty chemicals

"Easy to use, need a bit of training from the vendor, which is available 24/7. Gives quick separation of peaks, uses a low-volume gradient unit with 4-solvent low-pressure gradient analysis. Ideal for method development, wide range of analysis."

Review date: 27 Jan 2016 | Nexera X2 UHPLC

  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: JRFAmerica



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Residue and Metabolism Chemistry

"This system is excellent and easy to work and troubleshoot with almost no carry over issues. All parts are easy to access and repair. It is user friendly in every aspect. I recommend this system as a front end for any Mass Spec, with any detector."

Review date: 23 Mar 2015 | Nexera X2 UHPLC
Shimadzu’s Nexera X2 Series delivers superior, real-world performance across a wider application range while delivering unparalleled flexibility and reliability in HPLC/UHPLC analyses.

Like its predecessor, the Nexera X2 is optimized to enable analysis at pressures up to 19,000 psi without compromising performance and data quality. Nexera X2 autosamplers provide near-zero carryover, support ultrafast analysis with the world’s fastest cycle time (14 secs), and deliver excellent injection reproducibility down to 0.1µL injection volumes. In addition, the Nexera X2 systems can be configured with a variety of solvent delivery units and column ovens to meet any laboratory workflow.

The modular nature of Nexera X2 allows a solvent blending function that can mix up to 4 solvents per pump at a desired ratio, allowing you to change the proportion of the mobile phase components from run to run so there is no solvent wasted. This function also speeds up method development by automating solvent dilution, buffer pH adjustment, and modifier addition for optimizing separations.


Nexera X2 Features:

  • New PDA detector–offers superior sensitivity and resolution, achieving a 0.4×10-5 AU noise level for genuine UHPLC analysis
  • Automated solvent blending and method scouting–ideal for method development
  • Intelligent Peak Deconvolution Analysis (i-PDeA) function–unique software solution to separate and accurately integrate co-eluting peaks
  • Intelligent Dynamic Range Extension Calculator (i-DReC)–extends the dynamic range so low concentration (trace or impurity compounds) and very high concentration samples can be accurately analyzed in a single injection
  • Ultrahigh-throughput and clean autosampler–perfect front-end systems for any LCMS applications