NanoDrop™ 2000/c Spectrophotometers

The NanoDrop 2000/c are microvolume spectrophotometers for measuring DNA, RNA, and protein.As the industry leader in micro-sample quantitation, Thermo Scientific NanoDrop products meet the needs of today’s laboratory scientist— instruments that are smart, simple and robust. Thermo Scientific combines their extensive expertise in micro-sample analysis with an in-depth understanding of real-life applications to deliver the latest in UV-Vis and Fluorescence instrumentation.Using the patented sample retention system the NanoDrop 2000 accurately measures samples as small as 0.5 µL, and reports sample concentration, purity ratios, and full spectral data.All NanoDrop products utilize a unique technology that allows a sample to be pipetted directly onto an optical measurement surfa...Read more

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Reviews

53 Scientists have reviewed this product


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Average Rating: 4.4

Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
Rating: 4.0
Ease of use
5 out of 5
After sales service
3 out of 5
Value for money
4 out of 5
  • Review date:30 Jun 2015

  • Application Area:The use is very simple, only need a bit of attention to avoid bubbles but it's fantastic to quantify

  • NanoDrop™ 2000/c Spectrophotometers

"With the NanoDrop 1000 it has become simple to quantify small doses of low concentration RNA . Avoiding waste of material"
Rating: 4.7
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
4 out of 5
  • Review date:16 Jan 2015

  • Application Area:Protein concentration from tumors

  • NanoDrop™ 2000/c Spectrophotometers

"This product makes it simple to determine the protein concentration of a tumor cell suspension and allows us to process, aliquot and freeze in a timely and efficient manner."
Rating: 4.0
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
3 out of 5
  • Review date:10 Nov 2014

  • Application Area: DNA, RNA, Protein & Cell Culture Measurements

  • NanoDrop™ 2000/c Spectrophotometers

"This product is handy and very easy to use. It offers quick and accurate readings. Out of the spectrometers that I used in the past, this is the most reliable machine I have ever used. Somebody can easily measure DNA, RNA of different forms and cell cultures without making a major physical change."
Rating: 4.7
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
5 out of 5
  • Review date:17 Oct 2014

  • NanoDrop™ 2000/c Spectrophotometers

"This is a valuable device with user friend software, very simple to work and accurate results and reproducible data."
Rating: 5.0
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
5 out of 5
  • Review date:16 Sep 2014

  • Application Area:Protein/RNA/DNA Quantification

  • NanoDrop™ 2000/c Spectrophotometers

"It is not complicated and can achieve very fast results. There is no need for additional equipment such as cuvettes. Software is intuitively designed and is ideal for small quantities, such as nano drops. I have had the machine for three years and I have had no problems with it. I have only ever had positive experiences with the distributor too (peqlab)."
Rating: 3.7
Ease of use
5 out of 5
After sales service
3 out of 5
Value for money
3 out of 5
  • Review date:22 Apr 2014

  • Application Area: Measuring Nucleic Acids Concentration

  • NanoDrop™ 2000/c Spectrophotometers

"Nanodrop has become a common lab item for extensive use in measuring concentration of biomolecules. The ease of use, no need for cuvettes and need of low volumes was unprecedented and was the reason of nanodrop success. However, the issues of reproducibility and reliability remain a big concern. "
Rating: 4.3
Ease of use
4 out of 5
After sales service
5 out of 5
Value for money
4 out of 5
  • Review date:23 Dec 2013

  • Application Area:Molecular Biology

  • NanoDrop™ 2000/c Spectrophotometers

"This nano-drop has 8 pedestals which is great for running multiple samples. After having this instrument for a few years I saw that it wasn't producing consistent results. I would load the same samples multiple times (making sure they were homogenous and freshly mixed) and I would get substantial differences in results. I called the support line and the people were very friendly, helpful and followed up. They sent us a reconditioning kit, which we applied immediately and it seemed to take care of the problem. Make sure you always run your samples in duplicate to make sure your machine is consistent. The machine and it's accompanying software are pretty easy to use. We like this device a lot and would recommend it. You do have to make sure you have good technique and that you are able to load all 8 samples fast enough before any of your samples evaporate- causing a failure. With this device I highly recommend reading the instruction manual."
Rating: 3.7
Ease of use
4 out of 5
After sales service
3 out of 5
Value for money
4 out of 5
  • Review date:11 Dec 2013

  • Application Area:Spectrophotometer

  • NanoDrop™ 2000/c Spectrophotometers

"The "Nanodrop nd 1000" and the Software is very easy to handle. The documentation of the results is pretty easy. But I think the nanodrop has one weak point, the range (raw 340 sometimes has a too big measurement of the range). However it is a nice product."
Rating: 4.3
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:07 Aug 2013

  • Application Area:Protein quantification, nucleic acid quantification

  • NanoDrop™ 2000/c Spectrophotometers

"Very useful device with small sample volumes. The device is a number of years old and still working well. The pedestal is easy to clean, and the R/DNA values are very repeatable. The protein results are variable, but that is to be expected."
Rating: 3.7
Ease of use
4 out of 5
After sales service
3 out of 5
Value for money
4 out of 5
  • Review date:28 Jun 2013

  • Application Area:RNA/DNA Quantification

  • NanoDrop™ 2000/c Spectrophotometers

"Very easy to use, and does not take much instruction prior to first use. Fast analysis and simple software, with easy-to-understand readout. I would recommend this to a colleague."
Rating: 4.0
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:26 Jun 2013

  • Application Area:Biochemistry and RNA/DNA Quantification

  • NanoDrop™ 2000/c Spectrophotometers

"Easy to use, with clear directions. Easy to clean and little to no problems related to malfunctions with computer technology. When using this instrument for determining the concentration of RNA or DNA in a sample, the directions are straight forward and the numbers are clearly presented. I would recommend this product to future colleagues as well as other students that need to use it."
Rating: 4.0
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:26 Jun 2013

  • Application Area:ISO Extraction

  • NanoDrop™ 2000/c Spectrophotometers

"It is an excellent product. The services of this equipment are excellent. The quality is very good and all of our clients are very comfortable with this equipment."
Rating: 4.7
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
5 out of 5
  • Review date:03 Jun 2013

  • Application Area:DNA and RNA

  • NanoDrop™ 2000/c Spectrophotometers

"This spectrophotometer is very easy to use for measuring DNA and RNA concentration. You only need take 1µl from your samples and you can know the concentration within seconds. It's also very easy to clean."
Rating: 4.0
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
3 out of 5
  • Review date:28 May 2013

  • Application Area:nanotechnology

  • NanoDrop™ 2000/c Spectrophotometers

"This instrument is very interesting for nanotechnology, mainly for use the characterization of gold and silver nanoparticles in solution. I have been looking to understand your performance and calculate figures of merit such as selectivity, sensibility, limit of detection and quantification, robust, and others."
Rating: 5.0
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
5 out of 5
  • Review date:28 May 2013

  • Application Area:nucleic acid analysis

  • NanoDrop™ 2000/c Spectrophotometers

"This product is really good, especially small and very convenient to use.  We are using this product for measuring PCR products after PCR or DNA or RNA analysis after ethanol precipitation and gel extraction.  The quality of data is very good and excellent.  It's really good for requiring small amount of samples."
Rating: 3.7
Ease of use
4 out of 5
After sales service
5 out of 5
Value for money
2 out of 5
  • Review date:23 May 2013

  • Application Area:protein quantitation

  • NanoDrop™ 2000/c Spectrophotometers

"This product was a little pricey but is easy to use even for undergraduates. It is a solid performer and works well every time. We have been pleased with its stability. All in all, worth the extra money."
Rating: 5.0
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
5 out of 5
  • Review date:20 May 2013

  • Application Area:DNA/Protein analysis

  • NanoDrop™ 2000/c Spectrophotometers

"The NanoDrop 2000 is an excellent, easy-to-use instrument that makes DNA/Protein quantification a pleasure.  We are a teaching institution, so the NanoDrop is a perfect tool for allowing our students to quantitate and evaluate the quality of the DNA and proteins that they purify.  The most attractive features of the NanoDrop are the small volumes of sample required for analysis (as little as 1 microL) and the fact that no cuvettes are required.  The instrument itself is easy to use and the software that accompanies it for control and data analysis is very user friendly.  This is one of the best pieces of equipment that our lab has purchased!"
Rating: 4.0
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:18 Mar 2013

  • Application Area:Neurotransmitter-electrochemistry

  • NanoDrop™ 2000/c Spectrophotometers

"It was easy to use, user friendly, and saves lots of time. In the field of neurotransmitters and RNA/DNA where small amounts of samples are used the Nanodrop spectrophotometer is really useful."
Rating: 4.3
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
5 out of 5
  • Review date:18 Mar 2013

  • Application Area:DNA/RNA CONC.

  • NanoDrop™ 2000/c Spectrophotometers

"This spectrophotometer is miniature, easy to use, saves samples and time. Excellent at saving space in the lab, and most of all affordable."
Rating: 4.7
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
4 out of 5
  • Review date:30 Jan 2013

  • Application Area:Spectrophotometry

  • NanoDrop™ 2000/c Spectrophotometers

"On the plus side, this spectrophotometer is very simple to use, can measure as little as 10 ng/microl of DNA (the manufacturer advertise 2 ng/microl, but in my hands the measurements are not to be trusted at concentrations below 10 ng/microl), and does not require prior dilution of the sample (1 microl is needed for the measurement). On the minus side, the sample needs to be of high purity in aqueous solution devoid of surfactant (for example no SDS). In this regard, I have found this spectrophotometer not well suited for protein concentration measurements."
Rating: 5.0
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
5 out of 5
  • Review date:06 Sep 2012

  • Application Area:Protein science

  • NanoDrop™ 2000/c Spectrophotometers

"The single channel nanodrop is quick and easy to use, informing you of the concentration of your sample within just a few seconds, therefore it's possible to determine concentrations of many different samples quickly. When repeating same samples, concentration is usually extremely accurate and therefore a trustworthy and reliable machine."
Rating: 4.3
Ease of use
5 out of 5
After sales service
3 out of 5
Value for money
5 out of 5
  • Review date:28 Jun 2012

  • Application Area:DNA concentration

  • NanoDrop™ 2000/c Spectrophotometers

"I like how easy it is to use but I would like the 'data export' function to be more visible, otherwise it works very well."
Rating: 4.0
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
3 out of 5
  • Review date:11 Jun 2012

  • Application Area:DNA & RNA measurement

  • NanoDrop™ 2000/c Spectrophotometers

"Compact and easy to use. Only requires a small amount of sample. However the price is high and it can only run one sample at a time. Also in order to get repairs or service it needs to be shipped back to manufacturers."
Rating: 5.0
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
5 out of 5
  • Review date:17 May 2012

  • Application Area:Protein, DNA & RNA Measurements

  • NanoDrop™ 2000/c Spectrophotometers

"Very easy to operate, even for first time user. Only a small volume of sample is required. The software-user interface is straight forward and easy to follow."
Rating: 4.3
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:20 Apr 2012

  • Application Area:Protein and Nucleic Acid Quantification

  • NanoDrop™ 2000/c Spectrophotometers

"A very user-friendly interface with good details and walk-throughs for various protocols and applications. Easy to get up and running in a few minutes. Data is displayed in a very clear format. Easy to customize and save my own protocols, data, etc. I can tweak methods very precisely and easily. Changes are easy to detect. I have some difficulty with reproducibility - some sample measurements have to be thrown out for no apparent reason. The instrument has to be recalibrated frequently."
Rating: 4.3
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:23 Mar 2012

  • Application Area:DNA concentration

  • NanoDrop™ 2000/c Spectrophotometers

"Very small sample size, easy calibration and wide dynamic range. No need to dilute samples, can do oligonucleotides. Protein, double stranded DNA, wide range of applications."
Rating: 4.7
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
5 out of 5
  • Review date:23 Mar 2012

  • Application Area:Protein detection

  • NanoDrop™ 2000/c Spectrophotometers

"Very easy to use and fast sample time. Program on computer is very good and easy to use. Only need to use minimum sample volume which is very convenient. It's small, does not take much space and is very easy to manage/clean."
Rating: 4.0
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:23 Mar 2012

  • Application Area:UV-VIS small sample volume

  • NanoDrop™ 2000/c Spectrophotometers

"Easy to use and quantitative. Limitations: It can't be read when there is an air bubble in it and there is no temperature control. It can only do samples, one by one, and there is no array detection."
Rating: 4.7
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
5 out of 5
  • Review date:23 Mar 2012

  • Application Area:Protein detection/quantitation

  • NanoDrop™ 2000/c Spectrophotometers

"This is easy to use and the device is a great addition to any lab. The small sample size makes this device applicable to many of our small volume microfluidic samples."
Rating: 4.3
Ease of use
5 out of 5
After sales service
3 out of 5
Value for money
5 out of 5
  • Review date:21 Mar 2012

  • Application Area:Biochemistry

  • NanoDrop™ 2000/c Spectrophotometers

"This equipment is easy to use and does not require training. We purchased it four years ago and it is still working fine. The calibration requires the purchase of a calibration fluid but is easy to do."
Rating: 4.3
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:23 Jan 2012

  • NanoDrop™ 2000/c Spectrophotometers

"Nanodrop provides a quick and accurate method to assay protein, DNA and cell counting. Very easy interface. Instrument is small and connects via desktop and laptop."
Rating: 4.3
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money
3 out of 5
  • Review date:19 Dec 2011

  • NanoDrop™ 2000/c Spectrophotometers

"An absolute joy to use, it hasn't failed yet, however it doesn't replace a standard UV-VIS spec. You 'could' take the same measurements with a conventional spec- which gives better measurements- but requires a larger sample size."
Rating: 4.0
Ease of use
5 out of 5
After sales service
3 out of 5
Value for money
4 out of 5
  • Review date:26 Apr 2011

  • NanoDrop™ 2000/c Spectrophotometers

"Easy to use and great across many applications. Be sure to calibrate whenever results become untrustworthy as it will occasionally fall out of line, but calibration will bring it right back in."

Description

The NanoDrop 2000/c are microvolume spectrophotometers for measuring DNA, RNA, and protein.

As the industry leader in micro-sample quantitation, Thermo Scientific NanoDrop products meet the needs of today’s laboratory scientist— instruments that are smart, simple and robust. Thermo Scientific combines their extensive expertise in micro-sample analysis with an in-depth understanding of real-life applications to deliver the latest in UV-Vis and Fluorescence instrumentation.

Using the patented sample retention system the NanoDrop 2000 accurately measures samples as small as 0.5 µL, and reports sample concentration, purity ratios, and full spectral data.

All NanoDrop products utilize a unique technology that allows a sample to be pipetted directly onto an optical measurement surface. The system uses inherent surface tension to hold a micro-volume sample in place during the measurement cycle. Once the measurement is complete, the surfaces are simply wiped with a lint-free lab wipe.


Features:

  • Fast measurement time of less than 5 seconds – just pipette, measure, and wipe clean.
  • Measure 0.5 - 2 µL DNA, RNA, and protein samples.
  • Software includes pre-configured methods for measuring nucleic acids, Protein A280 and colorimetric assays, and flexible customized methods.
  • Measure concentrations up to 15,000 ng/µl (dsDNA) - eliminating the need for dilutions.
  • Low-cost operation – no plates or other consumables.
  • Perfect for proteins with low wavelength absorbance, such as peptides at 205 nm.
  • No dilutions required, even for highly concentrated samples.
  • Easy to use—pipet sample directly onto the pedestal.
  • User-friendly software that includes custom methods and data export capabilities.

Product Overview

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NanoDrop™ 2000/c Spectrophotometers

by Thermo Fisher Scientific

4.4/5.0 (53 reviews)
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money
4 out of 5






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