Macrocycle Library
ChemBridge has developed a diverse, easily modifiable collection of macrocycles intended to be accessible to both industry and academic researchers. The Macrocycle Library compounds are based on a collection of novel synthetic macrocyclic scaffolds with some based on natural products. ChemBridge chemists developed synthetic strategies for the synthesis and functionalization of macrocyclic compounds and to date have developed o…
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ChemBridge has developed a diverse, easily modifiable collection of macrocycles intended to be accessible to both industry and academic researchers. The Macrocycle Library compounds are based on a collection of novel synthetic macrocyclic scaffolds with some based on natural products. ChemBridge chemists developed synthetic strategies for the synthesis and functionalization of macrocyclic compounds and to date have developed over 70 core macrocyclic scaffolds.
Brochures
Macrocycle Library: Macrocyclic Compounds for Challenging Targets
This brochure discusses the growing popularity of using synthetic macrocycles for low druggability targets such as antimicrobial, antiviral and protein-protein interaction. It goes onto describe the ChemBridge Macrocycle Library, diverse, easily modifiable collection of over 6000 macrocycles intended to be accessible to both industry and academic researchers. The brochure includes how the Library was development and the general characteristics of the compounds.
Learn More About ChemBridge: Corporate Profile
Interested in learning more about ChemBridge, check out their corporate profile.
Leveraging ChemBridge Libraries in Cancer Research
More than 1,500 articles cite the use of ChemBridge® small molecule screening libraries and compounds in a wide variety of research areas using high-throughput screening or focused screening following computer-aided screening. The list below highlights a small sampling of articles, from 2014 to present, that focus on work in cancer research and provides a sample of the different techniques employed and targets explored in hit finding and probe discovery using ChemBridge libraries and compounds.
ChemBridge Launches New Library of Synthetic Macrocycles
New collection of macrocyclic compounds is designed for hit-finding against difficult targets including antiviral and protein-protein interaction targets.
