Thermo Scientific™ Orbitrap Velos Pro hybrid MS

4.3
/
5.0
  |  11 reviews


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Average Rating: 4.3
11 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


Rating: 4.0

"It has amazingly high spectral resolution and mass accuracy. Allows the determination of intact mass for proteins even with 150kDa molecular weight via spectral deconvolution. For smaller proteins (molecular weight less than 35-40 kDa) monoisotopic resolution can be obtained, allowing quantitation of isoforms based on their relative intensities. It is relatively expensive, but it's worth the investment as one can obtain such results as never ever before. Ever since we have bought the instrument it has helped to solve many of our previous analytical problems. Coupled to ultra high performance liquid chromatography (especially comprehensive 2D-UPLC as in our laboratory) it can further enhance the usability. When one has such an expensive investment it is crucial to get the most information possible. We have carefully chosen the best instrumentation to meet our needs."

Review date: 27 Aug 2013 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Upenn



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Proteomics

"We have had great experience so far with Orbitrap Velos Pro. It is stable and sensitive."

Review date: 12 Aug 2013 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Texas Tech University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Glycomic study

"High sensitivity and high selectivity allows detection of unknown materials. Easy to use, easy operation manual and automatic sequence. High maintenance fee for minor problems."

Review date: 21 May 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: University of Notre Dame



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Proteomics

"An easy way to detect peptides in electropohoresis. A very useful tool in proteomics. Has good stability and reproducibility."

Review date: 16 May 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: University of Notre Dame



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Proteomics

"Very easy to use, a perfect mass spectrometer for protein analysis. A high accuracy instrument for analysing complex protein samples. The after sales service is very good."

Review date: 26 Apr 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS


  • Status:

    Reviewer

  • Member since: 2010

  • Organization: University of Notre Dame



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Proteomics

"The Orbitrap Velos is far one of the fastest mass spectrometers and is able to be coupled to capillary electrophoresis. Calibration is not hard but still takes a while and has to be done every two weeks. Electronic board burnt down twice in our first year's use."

Review date: 26 Mar 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Banyan Biomarkers



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Proteomics

"Very reliable and very easy to use. Customer service is great always available to assist to our needs."

Review date: 26 Mar 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: U.S. Pharmacopeia



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

  • Application Area:Compendial Sciences

"Best in class resolution >50,000. Good mass range, looks at a broad range of molecule types. Great problem solving tool and support for LC method development."

Review date: 23 Mar 2012 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2004

  • Organization: Wageningen University



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"Works well and easy to use."

Review date: 18 Aug 2011 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Centers for Disease Control and Prevention



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Rating: 3.3
"good but expensive."

Review date: 08 Jun 2011 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Centers for Disease Control



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"Does things other high RES instruments can't. Intensive training necessary."

Review date: 28 Apr 2011 | Thermo Scientific™ Orbitrap Velos Pro hybrid MS
Analyze proteomics and metabolomics samples rapidly and with confidence using the Thermo Scientific™ Orbitrap Velos Pro™ Hybrid Ion Trap-Orbitrap Mass Spectrometer.

This instrument combines a Thermo Scientific™ Orbitrap ™ mass analyzer and Velos Pro ion trap technology to deliver high resolution, speed, sensitivity, and flexibility.


Thermo Scientific Orbitrap Velos Pro hybrid MS Features:

  • Resolving power up to 100,000 FWHM and mass accuracy better than 1ppm RMS provide confidence when analyzing complex samples
  • Multiple fragmentation techniques—CID, HCD, and optionally ETD—offer versatility and facilitate structural characterization
  • Fast scanning and parallel MS and MSn analysis speeds analyses
  • Ion optics with novel neutral-blocking technology increase robustness
  • Collision cell with axial field gradient improves quantitative results
  • High mass resolution and mass accuracy enable high-confidence molecular weight determination of intact proteins, peptide identification in complex samples and analysis of isobaric species
  • High sensitivity increases detection of low-abundance peptides and proteins
  • Short duty cycle increases sequence coverage within in a single experiment
  • Stability, mass accuracy and wide dynamic facilitate label-free quantification
  • Mass resolution and mass accuracy distinguish between heavy and light peptide ion pairs and interferences in SILAC experiments
  • HCD cell with axial field improves quantification of isobarically labeled peptides
  • Optional electron-transfer dissociation (ETD) generates complementary information for P™ analyses and de novo sequencing
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Thermo Scientific™ Orbitrap Velos Pro hybrid MS

Manufacturer Thermo Fisher Scientific

4.3 / 5.0 | 11 reviews