Convenient and reliable concentration, purification, and diafiltration of 20 to 60 mL biological samples with Pall Life Science's Jumbosep Advance Centrifugal Devices
Features of the Macrosep Advance Centrifugal Devices:
• Typically concentrates 60 mL sample volumes to 5 mL in 30 minutes. • Provides high recoveries, typically > 90%. • Low protein-binding Omega membrane and polypropylene housing minimize losses due to non-specific binding. • Versatile Omega membrane is available in a variety of MWCOs. • Built-in deadstop prevents spinning to dryness. • Unique sealing mechanism prevents retentate leakage and filtrate contamination. • Economical. Sample reservoir and filtrate receiver can be sanitized or autoclaved, and reused.
The Jumbosep centrifugal devices replace dialysis, chemical precipitation, and lyophilization in the following applications: • Concentrating and desalting proteins. • Exchanging buffer or removing salt from chromatography eluates and gradient fractions. • Separating biomolecules from cell culture supernatants. • Concentrating or removing viruses. • Performing crude fractionation of dilute protein mixtures. • Removing debris and particulates from cell lysates.
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