The Thermo Scientific IonPac® ICE-AS6 ion-exclusion column is designed for fast analysis of aliphatic organic acids (including hydroxyl-substituted organic acids) and alcohols in complex or high-ionic-strength samples, including foods and beverages, biological samples, fermentation baths, industrial process liquors, and wastewaters. The ICE-AS6 column is ideally suited for most applications performed on the ICE-AS1 column.
The ICE-AS6 column provides improved peak efficiencies and selectivity for carboxylic acids and alcohols. The weakly ionized acids are separated by pKa differences, size, and hydrophobicity. Strong acid anions such as chloride, oxalate, and sulfate elute in the void and do not interfere with the quantification of the organic acids.
The ICE-AS6 column can be used with any typical strong acid eluent and a wide range of detectors, including conductivity, amperometry, photometry, and refractive index to determine aliphatic organic acids. Use the AS11 for fast analysis of organic acids and inorganic anions in well-characterized samples. Use the high-capacity IonPac AS11-HC column for organic acids and inorganic anions in complex sample matrices or uncharacterized samples.