EZ-2 Series

Solvent removal is an essential process for sample preparation across a range of applications in many industries. Many sample formats and solvents are used with no single technique providing a universal solution, but despite the variety of specifics evaporation is well-understood and relatively uncomplicated.

Several non-spectroscopic methods are currently used for the detection of algal toxins in water and most published studies utilize solid-phase extraction (SPE) as a sample preparation technique. However, this technique can be time consuming. In this application note, direct solvent evaporation using the Genevac EZ-2 evaporator is evaluated as a means to reduce to improve detection efficiency. It was found that this method improved reproducibility, decreased analysis time and reduced the risk of cross contamination when compared to SPE.

This application report describes a procedure, based on a semi-preparative LC-MS-MS system, for the determination of the biological activity and the definitive structure of metabolites in vitro assays or in vivo studies.

This application report assesses the suitability of the Genevac EZ-2 centrifugal vacuum evaporator for sample preparation while investigating the potential for cross contamination using a hair alcohol marker and a drugs of abuse (DoA) solution. The recovery of amphetamine is also evaluated.

When introducing any new piece of instrumentation or equipment into a highly controlled environment such as an environmental analysis laboratory, the new unit should be validated to ensure that it has equivalent or better performance to the existing equipment. Any impact on the testing methods can then be fully understood and the testing methods re-validated if necessary. With regard to sample concentration and evaporation technology the most important issue is sample recovery, especially for very volatile analytes. This application note describes Laboratoire départemental d’analyses de la Drôme’s (LDA26’s) evaluation of the Genevac EZ-2 and a comparison of two existing methodologies.

Read this case study and learn how the analysis of hair can be a useful tool in many forensic and clinical applications to establish drug use, trends of use and in the assessment of chronic alcohol consumption. Using the Genevac evaporation programme within these DoA produces, enables the excellent recovery of amphetamine, for example, which is renowned for its volatility.

Watch this video to learn how the EZ2 Elite from Genevac offers safe and efficient evaporation of your solvents in a compact design that is resistant to most acids even TFA. Specialist models resistant to hydrochloric acid are also available to suit the needs of your research. The Genevac Scroll Pump allows you to reach very low pressures, and so very high boiling point solvents like DMSO can be evaporated, which is not possible on other EZ2 models.

Watch this video to discover the EZ-2 Series Evaporator from Genevac. The EZ-2 Series has been designed specifically for solvent removal in many areas of scientific research, whether concentration of samples or complete drying is required. The EZ-2 Elite is recommended for solvents with boiling points up to 220°C.

Versatile evaporator available in different optimized configurations